The canonical Wnt–β-catenin pathway is a complex, evolutionarily conserved signalling
mechanism that regulates fundamental physiological and pathological processes. Wnt–β …

The Wnt/β-catenin signaling pathway exerts integral roles in embryogenesis and adult
homeostasis. Aberrant activation of the pathway is implicated in growth-associated diseases …

Abstract N6‐methyladenosine (m6A) is an abundant nucleotide modification in mRNA,
known to regulate mRNA stability, splicing, and translation, but it is unclear whether it is also …

Besides its important role in embryonic development and homeostatic self-renewal in adult
tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory …

Many transcription factors play a key role in cellular differentiation and the delineation of cell
phenotype. Transcription factors are regulated by phosphorylation, ubiquitination …

Cellular homeostasis and adaptation to various environmental conditions are importantly
regulated by the sophisticated mechanism of autophagy and its crosstalk with Wnt signaling …

The gene expression programs that define the identity of each cell are controlled by master
transcription factors (TFs) that bind cell-type-specific enhancers, as well as signaling factors …

Developmental signaling pathways control a vast array of biological processes during
embryogenesis and in adult life. The WNT pathway was discovered simultaneously in …

The liver is an organ that performs a multitude of functions, and its health is pertinent and
indispensable to survival. Thus, the cellular and molecular machinery driving hepatic …

Mesenchymal stromal cells (MSCs) are promising candidates for tissue engineering and
regenerative medicine. The multipotent stem cell component of MSC isolates is able to …