Abstract Alzheimer's disease (AD), a persistent neurological dysfunction, has an increasing
prevalence with the aging of the world and seriously threatens the health of the elderly …

Alzheimer's Disease (AD) is a global chronic disease in adults with beta-amyloid (Aβ)
deposits and hyperphosphorylated tau protein as the pathologic characteristics. Although …

Piperine (PIP) is an active alkaloid of black and long peppers. An increasing amount of
evidence is suggesting that PIP and its metabolite's could be a potential therapeutic to …

Abstract Ethnopharmacological relevance Irvingia gabonensis (Aubry-Lecomte ex O'Rorke)
Baill., also known as “African mango” or “bush mango”, belonging to family Irvingiaceae, has …

The escalating focus on ageing-associated disease has generated substantial interest in the
phenomenon of cognitive impairment linked to diabetes. Hyperglycemia exacerbates …

To investigate the effect of piperine on pancreatic β cell apoptosis, mice were fed with high-
fat diet and injected with 40 mg/kg streptozotoci to establish diabetic model. The mice in the …

Aim Cyclophosphamide is an effective anti-tumor agent, however, it induces genomic
instability and tissue toxicity in clinical application. This study aims to evaluate the action of …

Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder characterized by
memory loss, cognitive deterioration, and neuropsychiatric symptoms. Various drug targets …

Oxidative stress plays an important role in the occurrence of neurodegenerative diseases.
Previous studies indicate a strong connection between oxidative stress, inappropriate …

With the rising prevalence of diabetes and its association with cognitive impairment, interest
in the use of dietary alkaloids and other natural products has grown significantly …