With the COVID-19 pandemic now ongoing for close to a year, people all over the world are
still waiting for a vaccine to become available. The initial focus of accelerated global …

Most existing vaccines for human use are administered by needle-based injection.
Administering vaccines needle-free intranasally has numerous advantages over by needle …

Exposure to aluminum chloride (AlCl 3) induces progressive multiregional
neurodegeneration in animal models by promoting oxidative stress and neuroinflammation …

The hypoimmunogenicity of tumors is one of the main bottlenecks of cancer immunotherapy.
Enhancing tumor immunogenicity can improve the efficacy of tumor immunotherapy by …

Exposure to elemental aluminum and its salts is unavoidable. Aluminum as a metal is
present in transport, construction, packaging, and electronic equipment. Aluminum salts are …

In recent decades, vaccines have been extraordinary resources to prevent pathogen
diffusion and cancer. Even if they can be formed by a single antigen, the addition of one or …

Purified vaccine antigens offer important safety and reactogenicity advantages compared
with live attenuated or whole killed virus and bacterial vaccines. However, they require the …

Autism spectrum disorder (ASD), schizophrenia, and bipolar disorder are genetically
complex and heterogeneous neurodevelopmental disorders (NDDs) resulting from genetic …

Adjuvants are a diverse family of substances whose main objective is to increase the
strength, quality, and duration of the immune response caused by vaccines. The most …

The increasing prevalence of allergic diseases demands efficient therapeutic strategies for
their mitigation. Allergen-specific immunotherapy (AIT) is the only causal rather than …