Spaceflight associated neuro-ocular syndrome (SANS) and the neuro-ophthalmologic effects of microgravity: a review and an update

AG Lee, TH Mader, CR Gibson, W Tarver, P Rabiei… - npj …, 2020 - nature.com
Prolonged microgravity exposure during long-duration spaceflight (LDSF) produces unusual
physiologic and pathologic neuro-ophthalmic findings in astronauts. These microgravity …

[HTML][HTML] Long-term human spaceflight and inflammaging: Does it promote aging?

M Capri, M Conte, E Ciurca, C Pirazzini… - Ageing Research …, 2023 - Elsevier
Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

[HTML][HTML] Effects of spaceflight on astronaut brain structure as indicated on MRI

DR Roberts, MH Albrecht, HR Collins… - … England Journal of …, 2017 - Mass Medical Soc
Background There is limited information regarding the effects of spaceflight on the
anatomical configuration of the brain and on cerebrospinal fluid (CSF) spaces. Methods We …

Head-down tilt bed rest studies as a terrestrial analog for spaceflight associated neuro-ocular syndrome

J Ong, AG Lee, HE Moss - Frontiers in Neurology, 2021 - frontiersin.org
Astronauts who undergo prolonged periods of spaceflight may develop a unique
constellation of neuro-ocular findings termed Spaceflight Associated Neuro-Ocular …

The effect of microgravity on the human venous system and blood coagulation: a systematic review

DS Kim, S Vaquer, L Mazzolai… - Experimental …, 2021 - Wiley Online Library
New Findings What is the central question of this study? Recently, an internal jugular
venous thrombus was identified during spaceflight: does microgravity induce venous and/or …

The short-term effects of sedentary behaviour on cerebral hemodynamics and cognitive performance in older adults: a cross-over design on the potential impact of …

CM Maasakkers, RJF Melis, RPC Kessels… - Alzheimer's Research & …, 2020 - Springer
Background Sedentary behaviour might be a potential risk factor for cognitive decline.
However, the short-term effects of sedentary behaviour on (cerebro) vascular and cognitive …

Persistent deterioration of visuospatial performance in spaceflight

E Takács, I Barkaszi, I Czigler, LG Pató, A Altbäcker… - Scientific Reports, 2021 - nature.com
Although human adaptation to spaceflight has been studied for decades, little is known
about its long-term effects on brain and behavior. The present study investigated …

Impacts of microgravity analogs to spaceflight on cerebral autoregulation

M Kermorgant, N Nasr, M Czosnyka… - Frontiers in …, 2020 - frontiersin.org
It is well known that exposure to microgravity in astronauts leads to a plethora physiological
responses such as headward fluid shift, body unloading, and cardiovascular deconditioning …

Postural influence on intracranial fluid dynamics: an overview

AF Sagirov, TV Sergeev, AV Shabrov, AY Yurov… - Journal of Physiological …, 2023 - Springer
This review focuses on the effects of different body positions on intracranial fluid dynamics,
including cerebral arterial and venous flow, cerebrospinal fluid (CSF) hydrodynamics, and …

Lower body negative pressure reduces optic nerve sheath diameter during head-down tilt

K Marshall-Goebel, R Terlević… - Journal of applied …, 2017 - journals.physiology.org
The microgravity ocular syndrome (MOS) results in significant structural and functional
ophthalmic changes during 6-mo spaceflight missions consistent with an increase in …