High on treatment platelet reactivity to aspirin and clopidogrel in ischemic stroke: a systematic review and meta-analysis

A Fiolaki, AH Katsanos, AP Kyritsis, S Papadaki… - Journal of the …, 2017 - Elsevier
Emerging studies highlight high on-treatment of platelet reactivity (HTPR) as a major
hindrance to the secondary prevention of cardiovascular ischemic events. The aim of this …

Platelet function/reactivity testing and prediction of risk of recurrent vascular events and outcomes after TIA or ischaemic stroke: systematic review and meta-analysis

ST Lim, V Thijs, SJX Murphy, I Fernandez-Cadenas… - Journal of …, 2020 - Springer
Background The prevalence of ex vivo 'high on-treatment platelet reactivity (HTPR)'and its
relationship with recurrent vascular events/outcomes in patients with ischaemic …

Aspirin resistance predicts unfavorable functional outcome in acute ischemic stroke patients

CW Wang, LL Su, QJ Hua, Y He, Y Fan, T Xi… - Brain research …, 2018 - Elsevier
Objective To investigate the prognostic value of aspirin reaction units (ARU) in a 3-month
follow-up study in a cohort of Chinese patients with first-ever ischemic stroke. Methods …

Interaction between COX-1 and COX-2 variants associated with aspirin resistance in Chinese stroke patients

X Yi, W Cheng, J Lin, Q Zhou, C Wang - Journal of Stroke and …, 2016 - Elsevier
Background There have been conflicting results for the association between
cyclooxygenase (COX) genetic variants and aspirin resistance (AR). The aim of this study …

[HTML][HTML] Biochemical aspirin resistance is associated with increased stroke severity and infarct volumes in ischemic stroke patients

X Cheng, NC Xie, HL Xu, C Chen, YJ Lian - Oncotarget, 2017 - ncbi.nlm.nih.gov
To explore the correlation of aspirin resistance (AR) with clinical stroke severity and infarct
volume using diffusion-weighted imaging (DWI) in 224 Chinese ischemic stroke patients …

Aspirin resistance affects medium-term recurrent vascular events after cerebrovascular incidents: A three-year follow-up study

A Wiśniewski, K Filipska, J Sikora, G Kozera - Brain Sciences, 2020 - mdpi.com
Background: The aim of this prospective, a three-year follow-up study, was to establish the
role of high on-treatment platelet reactivity (HTPR) in predicting the recurrence of vascular …

Interaction among COX-2, P2Y1 and GPIIIa gene variants is associated with aspirin resistance and early neurological deterioration in Chinese stroke patients

X Yi, C Wang, Q Zhou, J Lin - BMC neurology, 2017 - Springer
Background The effect of genetic variants on aspirin resistance (AR) remains controversial.
We sought to assess the association of genetic variants with AR and early clinical outcomes …

“Blueprinting” thrombogenicity and antithrombotic drug response at the bedside in patients presenting emergently with symptoms of acute stroke

KP Bliden, G Raviv, US Tantry, R Chaudhary… - Journal of Thrombosis …, 2019 - Springer
Early assessment of thrombogenicity and antithrombotic drug effects may be important for
therapeutic decision making in patients presenting with acute stroke. In this prospective …

Clinical significance of acute and serial platelet function testing in acute ischemic stroke

JT Kim, KH Choi, MS Park, JS Lee… - Journal of the …, 2018 - Am Heart Assoc
Background We sought to investigate the clinical implications of platelet reactivity to aspirin
and the variability in the platelet reactivity to aspirin during acute periods for the risk of …

High on‐treatment platelet reactivity is associated with poor outcomes after ischemic stroke: a meta‐analysis

K Zhou, S Yu, J Li, Y Tan, S Xing… - Acta Neurologica …, 2022 - Wiley Online Library
Objectives High on‐treatment platelet reactivity (HTPR) determined by platelet function
assays is present in certain patients with ischemic stroke or transient ischemic attack (TIA) …