Immunoinformatics-aided design of a peptide based multiepitope vaccine targeting glycoproteins and membrane proteins against monkeypox virus

N Akhtar, V Kaushik, RK Grewal, AK Wani… - Viruses, 2022 - mdpi.com
Monkeypox is a self-limiting zoonotic viral disease and causes smallpox-like symptoms. The
disease has a case fatality ratio of 3–6% and, recently, a multi-country outbreak of the …

Designing a novel multi‑epitope vaccine against Ebola virus using reverse vaccinology approach

M Alizadeh, H Amini-Khoei, S Tahmasebian… - Scientific reports, 2022 - nature.com
Ebola virus (EBOV) is a dangerous zoonotic infectious disease. To date, more than 25 EBOV
outbreaks have been documented, the majority of which have occurred in Central Africa …

T-cell epitope-based vaccine designing against Orthohantavirus: a causative agent of deadly cardio-pulmonary disease

A Joshi, NM Ray, J Singh, AK Upadhyay… - … Modeling Analysis in …, 2022 - Springer
Orthohantavirus, a zoonotic virus responsible for causing human cardio-pulmonary disease,
is proven to be a fatal disease. Due to the paucity of regimens to cure the disease and …

In silico design of a multi-epitope vaccine against HPV16/18

S Sanami, M Rafieian-Kopaei, KA Dehkordi… - BMC …, 2022 - Springer
Background Cervical cancer is the fourth most common cancer affecting women and is
caused by human Papillomavirus (HPV) infections that are sexually transmitted. There are …

An immunoinformatics study: designing multivalent T-cell epitope vaccine against canine circovirus

P Jain, A Joshi, N Akhtar, S Krishnan… - Journal of Genetic …, 2021 - Elsevier
Background Canine circovirus is a deadly pathogen of dogs and causes vasculitis and
hemorrhagic enteritis. It causes lethal gastroenteritis in pigs, fox, and dogs. Canine …

MERS virus spike protein HTL-epitopes selection and multi-epitope vaccine design using computational biology

A Joshi, N Akhtar, NR Sharma, V Kaushik… - Journal of …, 2023 - Taylor & Francis
MERS-CoV, a zoonotic virus, poses a serious threat to public health globally. Thus, it is
imperative to develop an effective vaccination strategy for protection against MERS-CoV …

Design of a multi-epitope vaccine against the pathogenic fungi Candida tropicalis using an in silico approach

N Akhtar, A Singh, AK Upadhyay… - Journal of Genetic …, 2022 - Elsevier
Background Candida tropicalis causes tropical invasive fungal infections, with a high
mortality. This fungus has been found to be resistant to antifungal classes such as azoles …

[PDF][PDF] Quercetin Compound Analysis to Develop Treatment for Dementia Associated with Alzheimer? s disease in Humans: Insilico Study

A Joshi, N Vats, H Singh, V Kaushik - Journal of Drug and Alcohol …, 2022 - researchgate.net
Background: Alzheimer's disease is a memory loss problem associated mostly with elderly
people, the cause of this disease is generally accumulation of beta-amyloid plaques around …

In-Silico Validation of Prosopis ciniraria Therapeutic Peptides Against Fungal Cell Wall: Better Treatment Strategy for Fungal Diseases

A Joshi, DS Solanki, P Gehlot, J Singh… - International Journal of …, 2022 - Springer
Prosopis cineraria commonly known as Druce are valuable herb that holds antibacterial
role, antifungal properties. We identified different peptides from this plant by deploying …

Immunoinformatics and computational approaches driven designing a novel vaccine candidate against Powassan virus

TL Nguyen, H Kim - Scientific Reports, 2024 - nature.com
Powassan virus (POWV) is an arthropod-borne virus (arbovirus) capable of causing severe
illness in humans for severe neurological complications, and its incidence has been on the …