Context-specific regulation of extracellular vesicle biogenesis and cargo selection
AC Dixson, TR Dawson, D Di Vizio… - … Reviews Molecular Cell …, 2023 - nature.com
To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …
other cells. An important aspect of cell–cell communication involves secretion of molecules …
Shedding light on extracellular vesicle biogenesis and bioengineering
F Teng, M Fussenegger - Advanced Science, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …
Quantitative proteomics identifies proteins enriched in large and small extracellular vesicles
A Lischnig, M Bergqvist, T Ochiya, C Lässer - Molecular & Cellular …, 2022 - ASBMB
There is a long-held consensus that several proteins are unique to small extracellular
vesicles (EVs), such as exosomes. However, recent studies have shown that several of …
vesicles (EVs), such as exosomes. However, recent studies have shown that several of …
Challenges and opportunities in exosome research—Perspectives from biology, engineering, and cancer therapy
ABSTRACT Exosomes are small ($30–140 nm) lipid bilayer-enclosed particles of
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …
endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most …
Intercellular transfer of activated STING triggered by RAB22A-mediated non-canonical autophagy promotes antitumor immunity
Y Gao, X Zheng, B Chang, Y Lin, X Huang, W Wang… - Cell Research, 2022 - nature.com
STING, an endoplasmic reticulum (ER) transmembrane protein, mediates innate immune
activation upon cGAMP stimulation and is degraded through autophagy. Here, we report that …
activation upon cGAMP stimulation and is degraded through autophagy. Here, we report that …
Dental enamel formation and implications for oral health and disease
Dental enamel is the hardest and most mineralized tissue in extinct and extant vertebrate
species and provides maximum durability that allows teeth to function as weapons and/or …
species and provides maximum durability that allows teeth to function as weapons and/or …
Tetraspanins in extracellular vesicle formation and function
Z Andreu, M Yáñez-Mó - Frontiers in immunology, 2014 - frontiersin.org
Extracellular vesicles (EVs) represent a novel mechanism of intercellular communication as
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …
vehicles for intercellular transfer of functional membrane and cytosolic proteins, lipids, and …
Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling
Exosomes are small endosome-derived extracellular vesicles implicated in cell–cell
communication and are secreted by living cells when multivesicular bodies (MVBs) fuse with …
communication and are secreted by living cells when multivesicular bodies (MVBs) fuse with …
Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
MF Baietti, Z Zhang, E Mortier, A Melchior… - Nature cell …, 2012 - nature.com
The biogenesis of exosomes, small secreted vesicles involved in signalling processes,
remains incompletely understood. Here, we report evidence that the syndecan heparan …
remains incompletely understood. Here, we report evidence that the syndecan heparan …