Histone post-translational modifications (HPTMs) are essential epigenetic mechanisms that
affect chromatin-associated nuclear processes without altering the DNA sequence. With the …

Dysfunctional mitochondrial quality control (MQC) is implicated in the pathogenesis of
Parkinson's disease (PD). The improper selection of mitochondria for mitophagy increases …

Objective Aberrant ketogenesis is correlated with the degree of steatosis in non-alcoholic
fatty liver disease (NAFLD) patients, and an inborn error of ketogenesis (mitochondrial HMG …

Acute pancreatitis and hyperamylasemia are often seen in patients with acute liver failure
(ALF). However, the underlying mechanisms remain elusive. This study describes …

Aging is accompanied by chronic low-grade inflammation, but the mechanisms that allow
this to persist are not well understood. Ketone bodies are alternative fuels produced when …

Previous studies have found that β-Hydroxybutyrate (BHB), the main component of ketone
bodies, is of physiological importance as a backup energy source during starvation or …

A growing body of evidence supports the beneficial effects of the ketone bodies (KBs),
acetoacetate and β-hydroxybutyrate (BHB), on diverse physiological processes and …

Diet and lifestyle factors greatly affect health and susceptibility to diseases, including cancer.
Stem cells' functions, including their ability to divide asymmetrically, set the rules for tissue …

Histones undergo a plethora of post-translational modifications (PTMs) that regulate
nucleosome and chromatin dynamics and thus dictate cell fate. Several evidences suggest …

Ketone bodies are short-chain fatty acids produced in the liver during periods of limited
glucose availability that provide an alternative energy source for the brain, heart, and …