Radiomics in nuclear medicine: robustness, reproducibility, standardization, and how to avoid data analysis traps and replication crisis

A Zwanenburg - European journal of nuclear medicine and molecular …, 2019 - Springer
Radiomics in nuclear medicine is rapidly expanding. Reproducibility of radiomics studies in
multicentre settings is an important criterion for clinical translation. We therefore performed a …

Quantitative radiomics studies for tissue characterization: a review of technology and methodological procedures

RTHM Larue, G Defraene… - The British journal of …, 2017 - academic.oup.com
Quantitative analysis of tumour characteristics based on medical imaging is an emerging
field of research. In recent years, quantitative imaging features derived from CT, positron …

[HTML][HTML] Machine learning methods for quantitative radiomic biomarkers

C Parmar, P Grossmann, J Bussink, P Lambin… - Scientific reports, 2015 - nature.com
Radiomics extracts and mines large number of medical imaging features quantifying tumor
phenotypic characteristics. Highly accurate and reliable machine-learning approaches can …

A radiomics model from joint FDG-PET and MRI texture features for the prediction of lung metastases in soft-tissue sarcomas of the extremities

M Vallières, CR Freeman, SR Skamene… - Physics in Medicine & …, 2015 - iopscience.iop.org
This study aims at developing a joint FDG-PET and MRI texture-based model for the early
evaluation of lung metastasis risk in soft-tissue sarcomas (STSs). We investigate if the …

CT-based radiomic signature predicts distant metastasis in lung adenocarcinoma

TP Coroller, P Grossmann, Y Hou… - Radiotherapy and …, 2015 - Elsevier
Background and purpose Radiomics provides opportunities to quantify the tumor phenotype
non-invasively by applying a large number of quantitative imaging features. This study …

Artificial intelligence in radiotherapy treatment planning: present and future

C Wang, X Zhu, JC Hong… - Technology in cancer …, 2019 - journals.sagepub.com
Treatment planning is an essential step of the radiotherapy workflow. It has become more
sophisticated over the past couple of decades with the help of computer science, enabling …

Robust radiomics feature quantification using semiautomatic volumetric segmentation

C Parmar, E Rios Velazquez, R Leijenaar… - PloS one, 2014 - journals.plos.org
Due to advances in the acquisition and analysis of medical imaging, it is currently possible
to quantify the tumor phenotype. The emerging field of Radiomics addresses this issue by …

The effect of SUV discretization in quantitative FDG-PET Radiomics: the need for standardized methodology in tumor texture analysis

RTH Leijenaar, G Nalbantov, S Carvalho… - Scientific reports, 2015 - nature.com
FDG-PET-derived textural features describing intra-tumor heterogeneity are increasingly
investigated as imaging biomarkers. As part of the process of quantifying heterogeneity …

Radiomic feature clusters and prognostic signatures specific for lung and head & neck cancer

C Parmar, RTH Leijenaar, P Grossmann… - Scientific reports, 2015 - nature.com
Radiomics provides a comprehensive quantification of tumor phenotypes by extracting and
mining large number of quantitative image features. To reduce the redundancy and compare …

A review on application of deep learning algorithms in external beam radiotherapy automated treatment planning

M Wang, Q Zhang, S Lam, J Cai, R Yang - Frontiers in oncology, 2020 - frontiersin.org
Treatment planning plays an important role in the process of radiotherapy (RT). The quality
of the treatment plan directly and significantly affects patient treatment outcomes. In the past …