Parkinson's disease is a neurodegenerative disease caused by the death of neurons, ie,
cells critical to the production of dopamine, an important neurotransmitter in the brain. Here …

Dopamine is a neurotransmitter that is produced in the substantia nigra, ventral tegmental
area, and hypothalamus of the brain. Dysfunction of the dopamine system has been …

Dopamine (DA) plays multiple roles in a wide range of physiological and pathological
processes via a large network of dopaminergic projections. To dissect the spatiotemporal …

Neuroscience is at a crossroads. Great effort is being invested into deciphering specific
neural interactions and circuits. At the same time, there exist few general theories or …

In younger adults, arousal amplifies attentional focus to the most salient or goal-relevant
information while suppressing other information. A computational model of how the locus …

For over two decades, fast-scan cyclic voltammetry (FSCV) has served as a reliable
analytical method for monitoring dopamine release in near real-time in vivo. However …

An essential approach for in vivo chemical monitoring is to use sampling probes coupled
with analytical methods; however, this method traditionally has limited spatial and temporal …

Mapping chemical dynamics in the brain of live subjects is a challenging but highly
rewarding goal because it allows neurotransmitter fluctuations to be related to behavior …

L-glutamine (Gln) is the most abundant amino acid in plasma and cerebrospinal fluid and a
precursor for the main central nervous system excitatory (L-glutamate) and inhibitory (γ …

Microfluidic and mass spectrometry (MS) methods are widely used to sample and probe the
chemical composition of biological systems to elucidate chemical correlates of their healthy …