Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response

R Tang, J Xu, W Wang, Q Meng, C Shao, Y Zhang… - Cell Reports …, 2023 - cell.com
The molecular dynamics of pancreatic ductal adenocarcinoma (PDAC) under chemotherapy
remain incompletely understood. The widespread use of neoadjuvant chemotherapy (NAC) …

Multiomics technologies for comprehensive tumor microenvironment analysis in triple-negative breast cancer under neoadjuvant chemotherapy

G Wang, Y Yao, H Huang, J Zhou, C Ni - Frontiers in Oncology, 2023 - frontiersin.org
Triple-negative breast cancer (TNBC) is one of the most aggressive breast cancer subtypes
and is characterized by abundant infiltrating immune cells within the microenvironment. As …

Forward single‐cell sequencing into clinical application: understanding of cancer microenvironment at single‐cell solution

X Liu, CA Powell, X Wang - Clinical and Translational Medicine, 2022 - Wiley Online Library
Single‐cell RNA sequencing (scRNA‐seq) is considered an important approach to
understand the molecular mechanisms of cancer microenvironmental functions and has the …

[HTML][HTML] Differential chromatin accessibility and transcriptional dynamics define breast cancer subtypes and their lineages

MD Iglesia, RG Jayasinghe, S Chen, NV Terekhanova… - Nature Cancer, 2024 - nature.com
Breast cancer (BC) is defined by distinct molecular subtypes with different cells of origin. The
transcriptional networks that characterize the subtype-specific tumor-normal lineages are not …

[HTML][HTML] Effectiveness of Chinese Herbal Medicine as a Complementary Treatment for Neutropenia Prevention and Immunity Modulation During Chemotherapy in …

KH Wang, HS Shen, SC Chu, TF Wang… - JMIR Research …, 2024 - researchprotocols.org
Background In recent years, advancements in cancer treatment have enabled cancer cell
inhibition, leading to improved patient outcomes. However, the side effects of chemotherapy …

Neo-peripheral adaptive immune score predicts neoadjuvant chemotherapy for locally advanced breast cancer

H Wang, X Sheng, T Yan, Y Xu, Y Wang, Y Lin… - Breast Cancer Research …, 2023 - Springer
Purpose Whether peripheral immune cell subsets can predict pathological complete
response (pCR) in breast cancer patients remains to be elucidated. We aimed to dissect the …

[引用][C] Gang Wang1, Yao Yao2, 3, 4, Huanhuan Huang2, 3, 4, Jun Zhou5 and Chao Ni2, 3, 4

G Wang, Y Yao, H Huang, J Zhou, C Ni - 2023 - europepmc.org
Triple-negative breast cancer (TNBC), defined by the absence of estrogen receptor (ER),
progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) …