Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Nanotechnology-based chemotherapeutics and imaging agents represent a new era of
“cancer nanomedicine” working to deliver versatile payloads with favorable …

Cell mass, volume and growth rate are tightly controlled biophysical parameters in cellular
development and homeostasis, and pathological cell growth defines cancer in metazoans …

H460 non-small cell lung, HCT116 colon and 4T1 breast tumor cell lines induced into
senescence by exposure to either etoposide or doxorubicin were able to recover …

High throughput drug screening is an established approach to investigate tumor biology and
identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not …

Cellular analysis plays important roles in various biological applications, such as cell
biology, drug development, and disease diagnosis. Conventional cellular analysis usually …

Viscoelasticity and its alteration in time and space has turned out to act as a key element in
fundamental biological processes in living systems, such as morphogenesis and motility …

Single cell analysis is an emerging field requiring a high level interdisciplinary collaboration
to provide detailed insights into the complex organisation, function and heterogeneity of life …

Quantitative phase microscopies (QPMs) play a pivotal role in bio-imaging, offering unique
insights that complement fluorescence imaging. They provide essential data on mass …

Cell mass and composition change with cell cycle progression. Our previous work
characterized buoyant mass dynamics in mitosis (Miettinen et al., 2019), but how dry mass …