Promising bioactive compounds from the marine environment and their potential effects on various diseases

A Karthikeyan, A Joseph, BG Nair - Journal of Genetic Engineering and …, 2022 - Elsevier
Background The marine environment hosts a wide variety of species that have evolved to
live in harsh and challenging conditions. Marine organisms are the focus of interest due to …

[HTML][HTML] l-carnitine: Nutrition, pathology, and health benefits

AH Alhasaniah - Saudi Journal of Biological Sciences, 2023 - Elsevier
Carnitine is a medically needful nutrient that contributes in the production of energy and the
metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat …

Dl-3-n-Butylphthalide (NBP): a promising therapeutic agent for ischemic stroke

S Wang, F Ma, L Huang, Y Zhang… - CNS & Neurological …, 2018 - ingentaconnect.com
Background and Objective: Stroke is a leading cause of morbidity and mortality in both
developed and developing countries all over the world. The only drug for ischemic stroke …

The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease

L Zuo, MS Motherwell - Gene, 2013 - Elsevier
The exact pathogenesis of Parkinson's disease (PD) is still unknown and proper
mechanisms that correspond to the disease remain unidentified. It is understood that PD is …

Multifunctional role of natural products for the treatment of Parkinson's disease: at a glance

MM Rahman, X Wang, MR Islam, S Akash… - Frontiers in …, 2022 - frontiersin.org
Natural substances originating from plants have long been used to treat neurodegenerative
disorders (NDs). Parkinson's disease (PD) is a ND. The deterioration and subsequent …

A review of recent advances in neuroprotective potential of 3‐N‐Butylphthalide and its derivatives

IA Abdoulaye, YJ Guo - BioMed research international, 2016 - Wiley Online Library
The research of alternative treatment for ischemic stroke and degenerative diseases has
always been a priority in neurology. 3‐N‐Butylphthalide (NBP), a family of compounds …

Neuroprotective effects of natural compounds on neurotoxin-induced oxidative stress and cell apoptosis

B Chen, J Zhao, R Zhang, L Zhang, Q Zhang… - Nutritional …, 2022 - Taylor & Francis
Objectives: Overproduction of reactive species, notably reactive oxygen (ROS) and nitrogen
(RNS) species, along with the failure of balancing effects of endogenous antioxidant …

Ellagic acid exerts protective effect in intrastriatal 6-hydroxydopamine rat model of Parkinson's disease: Possible involvement of ERβ/Nrf2/HO-1 signaling

T Baluchnejadmojarad, N Rabiee, S Zabihnejad… - Brain Research, 2017 - Elsevier
Parkinson's disease (PD) is a prevalent movement disorder in the elderly with progressive
loss of mesencephalic dopaminergic neurons and incapacitating motor and non-motor …

Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: the role of glia and NRf2 regulation

S Hernando, C Requejo, E Herran… - Neurobiology of …, 2019 - Elsevier
Omega-3 polyunsaturated fatty acids (n-3 PUFAs) have been widely associated to beneficial
effect over different neurodegenerative diseases. In the present study, we tested the …

Neuroprotective properties of the marine carotenoid astaxanthin and omega-3 fatty acids, and perspectives for the natural combination of both in krill oil

MP Barros, SC Poppe, EF Bondan - Nutrients, 2014 - mdpi.com
The consumption of marine fishes and general seafood has long been recommended by
several medical authorities as a long-term nutritional intervention to preserve mental health …