Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic review

CL Townsend, J O'Rourke, E Milanzi… - Journal of the …, 2022 - Wiley Online Library
Introduction Globally about 1.7 million children were living with HIV in 2020. Two integrase
strand transfer inhibitors, dolutegravir and raltegravir, are increasingly used in children. We …

Emergence of resistance in HIV-1 integrase with dolutegravir treatment in a pediatric population from the IMPAACT P1093 study

C Vavro, T Ruel, A Wiznia, N Montañez… - Antimicrobial agents …, 2022 - Am Soc Microbiol
ABSTRACT P1093 is a multicenter, open-label, phase I/II study of pharmacokinetics, safety,
and tolerability of dolutegravir plus an optimized background regimen in pediatric …

HIV in Neonates and Infants

AF Camacho-Gonzalez… - Clinics in …, 2021 - perinatology.theclinics.com
The initial recognition of AIDS in select populations in the early 1980s was soon recognized
to be an issue for the broader, general population. Early cases suggesting maternal-to-infant …

Integrase Strand Transfer Inhibitor Use in Children with Perinatal HIV-1 Infection: A Narrative Review

M Failla, E Pasquali, L Galli… - AIDS Research and …, 2023 - liebertpub.com
Integrase strand transfer inhibitors (INSTIs), including raltegravir (RAL), dolutegravir (DTG),
elvitegravir (EVG), bictegravir (BIC), and cabotegravir (CAB), are increasingly used, given …

[PDF][PDF] Effectiveness and safety of dolutegravir and raltegravir for treating children and adolescents living with HIV: a systematic

CL Townsend, J O'Rourke, E Milanzi, IJ Collins, A Judd… - 2022 - scienceopen.com
Abstract Introduction: Globally about 1.7 million children were living with HIV in 2020. Two
integrase strand transfer inhibitors, dolutegravir and raltegravir, are increasingly used in …