Human leukocyte antigen class I (HLA-I) molecules are encoded by major histocompatibility
complex (MHC) class I loci in humans. The binding and interaction between HLA-I …

SARS-CoV-2 variants that escape neutralization and potentially affect vaccine efficacy have
emerged. T cell responses play a role in protection from reinfection and severe disease, but …

Highlights•Mass cytometry's niche within cutting edge single cell analysis
methods.•Unbiased analysis of lymphoid and myeloid immune cell diversity.•Simultaneous …

The number of approved or investigational late phase viral vector gene therapies (GTx) has
been rapidly growing. The adeno-associated virus vector (AAV) technology continues to be …

Sequence homology between SARS-CoV-2 and common-cold human coronaviruses
(HCoVs) raises the possibility that memory responses to prior HCoV infection can affect T …

BACKGROUND Mosaic and consensus HIV-1 immunogens provide two distinct approaches
to elicit greater breadth of coverage against globally circulating HIV-1 and have shown …

Protein–protein interfaces play fundamental roles in the molecular mechanisms underlying
pathophysiological pathways and are important targets for the design of compounds of …

CD8+ T cell responses restricted by MHC-E, a nonclassical MHC molecule, have been
associated with protection in an SIV/rhesus macaque model. The biological relevance of …

Middle East respiratory syndrome coronavirus (MERS-CoV), a novel infectious agent
causing severe respiratory disease and death in humans, was first described in 2012 …

Small noncoding RNAs (sRNAs) from mRNA 3′ UTRs seem to present a previously
unrecognized layer of bacterial post-transcriptional control whereby mRNAs influence each …