Visible-to-NIR-light activated release: from small molecules to nanomaterials

R Weinstain, T Slanina, D Kand, P Klan - Chemical reviews, 2020 - ACS Publications
Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable)
protecting groups (PPGs), also known as caged or photocaged compounds, are used to …

Synthesis and derivatization of julolidine: a powerful heterocyclic structure

JOS Varejão, EVV Varejão… - European Journal of …, 2019 - Wiley Online Library
Julolidines constitute a class of N‐heterocycle compounds which have in common the 2, 3,
6, 7‐tetrahydro‐1H, 5H‐benzo [1, 2] quinolizine ring. Due mainly to its fluorescence …

Coumarin Photocaging Groups Modified with an Electron‐Rich Styryl Moiety at the 3‐Position: Long‐Wavelength Excitation, Rapid Photolysis, and Photobleaching

Q Lin, L Yang, Z Wang, Y Hua, D Zhang… - Angewandte Chemie …, 2018 - Wiley Online Library
A new class of coumarin photocaging groups modified with an electron‐rich styryl moiety at
the 3‐position was constructed. The large π‐conjugated structure and stabilization of the …

C (sp 3)–H cyclizations of 2-(2-vinyl) phenoxy-tert-anilines

P Dunkel, D Bogdán, R Deme, Á Zimber, V Ballayová… - RSC …, 2024 - pubs.rsc.org
1, 5-hydride transfer-triggered cyclization reactions offering a robust method for C (sp3)–C
(sp3) coupling and the synthesis of eg tetrahydroquinolines have been thoroughly …

Extending the Palette of Green Coumarin Photocages–Oligonucleotide Fragmentation and Superior 5'‐Caps

J Kaufmann, J Wolf, A Heckel - Chemistry–A European Journal, 2023 - Wiley Online Library
The possibilities of dicyanocoumarin (DCCM)‐modified oligonucleotides are expanded to
not just allow their release and therefore activation with green light (OFF→ ON) but to also …

Coumarin‐Derived Caging Groups in the Spotlight: Tailoring Physiochemical and Photophysical Properties

MR Clotworthy, JJM Dawson, MD Johnstone… - …, 2024 - Wiley Online Library
The development of light‐responsive molecular tools enables spatiotemporal control of
biochemical processes with superior precision. Amongst these molecular tools, photolabile …

Photoactivatable prodrugs of butyric acid based on new coumarin fused oxazole heterocycles

AMS Soares, G Hungerford, SPG Costa… - Dyes and …, 2017 - Elsevier
New coumarin fused oxazoles were investigated as photosensitive units for carboxylic acid
groups using butyric acid as a model compound. 6-Oxo-6H-benzopyrano [6, 7-d] oxazol-8 …

Phototriggered release of tetrapeptide AAPV from coumarinyl and pyrenyl cages

FC Santos, AMS Soares, MST Gonçalves, SPG Costa - Amino Acids, 2017 - Springer
Abstract Ala–Ala–Pro–Val (AAPV) is a bioactive tetrapeptide that inhibits human neutrophil
elastase, an enzyme involved in skin chronic inflammatory diseases like psoriasis. Caged …

Photoactivable heterocyclic cages in a comparative release study of butyric acid as a model drug

AM Piloto, G Hungerford, JU Sutter, AMS Soares… - … of Photochemistry and …, 2015 - Elsevier
Aim ng at the improvement of the photorelease of butyric acid–a model carboxylic acid drug,
a set of heteroaromatic compounds based on acridine, naphtho [2, 1-b] pyran, 3H …

Facile synthesis and characterization of indene-fused 4-methylcoumarins and an unexpected skeletal rearrangement via Pechmann condensation

J Wu, W Liu, L Liang, Y Gan, S Xia, X Gou, X Sun - Tetrahedron Letters, 2020 - Elsevier
The Pechmann condensation of phenolic fluorenes with ethyl acetoacetate afforded indene-
fused 4-methylcoumarins. In addition to the expected indeno [1, 2-g] coumarin, a skeletal …