Physical Activity and Cognitive Functioning

F Latino, F Tafuri - Medicina, 2024 - mdpi.com
Neuroscience applied to motor activity is a growing area that aims to understand the effects
of motor activity on the structures and functions of the Central Nervous System. Attention has …

[HTML][HTML] Emerging role of plant-based dietary components in post-translational modifications associated with colorectal cancer

C Rodríguez-García, F Gutiérrez-Santiago - Life, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancers worldwide. Its main modifiable
risk factors are diet, alcohol consumption, and smoking. Thus, the right approach through …

[HTML][HTML] Inhibition of Enzymes Involved in Neurodegenerative Disorders and Aβ1–40 Aggregation by Citrus limon Peel Polyphenol Extract

R Arcone, A D'Errico, R Nasso, R Rullo, A Poli… - Molecules, 2023 - mdpi.com
Alzheimer's (AD) and Parkinson's diseases (PD) are multifactorial neurogenerative
disorders of the Central Nervous System causing severe cognitive and motor deficits in …

Carbon monoxide releasing molecule-2 attenuates angiotensin II-induced IL-6/Jak2/Stat3-associated inflammation by inhibiting NADPH oxidase-and mitochondria …

CY Hsu, TTT Vo, CW Lee, YL Chen, WN Lin… - Biochemical …, 2022 - Elsevier
Abdominal aortic aneurysm (AAA) is a common inflammatory vascular disease. Angiotensin
II (Ang II) involves in AAA progression by promoting the proliferation and migration of …

[HTML][HTML] Identification and Characterization of Neuroprotective Properties of Thaumatin-like Protein 1a from Annurca Apple Flesh Polyphenol Extract

A D'Errico, R Nasso, A Di Maro, N Landi, A Chambery… - Nutrients, 2024 - mdpi.com
Background: Alzheimer's disease (AD) and Parkinson's disease (PD) are multifactorial
neurodegenerative disorders that are mostly treated with drugs inhibiting key enzymes of …

[HTML][HTML] Myogenesis in C2C12 Cells Requires Phosphorylation of ATF6α by p38 MAPK

V Pagliara, G Amodio, V Vestuto, S Franceschelli… - Biomedicines, 2023 - mdpi.com
Activating transcription factor 6α (ATF6α) is an endoplasmic reticulum protein known to
participate in unfolded protein response (UPR) during ER stress in mammals. Herein, we …

[HTML][HTML] SMAD7 Sustains XIAP Expression and Migration of Colorectal Carcinoma Cells

M Colella, A Iannucci, C Maresca, F Albano… - Cancers, 2024 - mdpi.com
Simple Summary Colorectal cancer (CRC) cells are characterized by high levels of SMAD7,
a protein involved in the positive control of growth and survival of cancer cells. This study …

[HTML][HTML] Effect of Hydroxytyrosol Derivatives of Donepezil on the Activity of Enzymes Involved in Neurodegenerative Diseases and Oxidative Damage

A D'Errico, R Nasso, R Rullo, J Maiuolo, P Costanzo… - Molecules, 2024 - mdpi.com
Monoamine oxidase and xanthine oxidase inhibitors represent useful multi-target drugs for
the prevention, attenuation, and treatment of oxidative damage and neurodegenerative …

Effect of kaempferol on the biological behavior of human colon cancer via regulating MMP1, MMP2, and MMP9

X Zhang, J Fan, F Guo, H Huang, J Xue… - Journal of …, 2022 - Wiley Online Library
Kaempferol is a kind of flavonoid, which has a significant anticancer effect. MMPs were
discovered with the function of cleaving the extracellular matrix. We utilized bioinformatics to …

Inhibition of Interleukin-6 Dependent Metalloproteinases-9/2 Expression in Cancer Cells by Diet Polyphenols

R Arcone, R Nasso, V Pagliara… - Anti-Inflammatory & …, 2023 - ingentaconnect.com
Among inflammatory cytokines, Interleukin-6 (IL-6) is one of the major activators of acute
phase response and is also involved in immune response and cancer progression. IL-6 is …