Atherosclerosis is characterized by the retention of modified lipoproteins in the arterial wall.
These modified lipoproteins activate resident macrophages and the recruitment of monocyte …

Sex and aging influence the human immune system, resulting in disparate responses to
infection, autoimmunity, and cancer. However, the impact of sex and aging on the immune …

Atherosclerotic vascular disease remains the most common cause of ischemia, myocardial
infarction, and stroke. Vascular function is determined by structural and functional properties …

Background: Long noncoding RNAs (lncRNAs) are important regulators of biological
processes involved in vascular tissue homeostasis and disease development. The present …

Oral epithelial cells discriminate between pathogenic and non-pathogenic stimuli, and only
induce an inflammatory response when they are exposed to high levels of a potentially …

Purpose: Lens epithelial cell (LEC) conversion to myofibroblast is responsible for fibrotic
cataract surgery complications including posterior capsular opacification. While transforming …

Whether bone marrow modulates systemic metabolism remains unknown. Here, we found
that (i) myeloid cell–specific myeloid-derived growth factor (MYDGF) deficiency exacerbated …

Neutrophils play a crucial role in the intertwined processes of thrombosis and inflammation.
An altered neutrophil phenotype may contribute to inadequate resolution, which is known to …

Background Endometrial cancer (EC) is one of the most common gynecological
malignancies globally, and the development of innovative, effective drugs against EC …

The hepatotoxicity of regorafenib is one of the most noteworthy concerns for patients,
however the mechanism is poorly understood. Hence, there is a lack of effective intervention …