Imaging, biomarker, and clinical predictors of cardiac remodeling in heart failure with reduced ejection fraction

A Aimo, HK Gaggin, A Barison, M Emdin, JL Januzzi - JACC: Heart Failure, 2019 - jacc.org
In response to injury, hemodynamic changes, or neurohormonal activation, the heart
undergoes a series of structural and functional changes that have been termed cardiac …

Usual and unusual care: existing practice control groups in randomized controlled trials of behavioral interventions

KE Freedland, DC Mohr, KW Davidson… - Psychosomatic …, 2011 - journals.lww.com
Objective: To evaluate the use of existing practice control groups in randomized controlled
trials of behavioral interventions and the role of extrinsic health care services in the design …

Head-to-head comparison of serial soluble ST2, growth differentiation factor-15, and highly-sensitive troponin T measurements in patients with chronic heart failure

HK Gaggin, J Szymonifka, A Bhardwaj, A Belcher… - JACC: Heart Failure, 2014 - jacc.org
Objectives: This analysis aimed to perform a head-to-head comparison of 3 of the promising
biomarkers of cardiovascular (CV) outcomes in heart failure (HF)—soluble ST2 (sST2) …

Use of amino-terminal pro–B-type natriuretic peptide to guide outpatient therapy of patients with chronic left ventricular systolic dysfunction

JL Januzzi, SU Rehman, AA Mohammed… - Journal of the American …, 2011 - jacc.org
Objectives: The aim of this study was to evaluate whether chronic heart failure (HF) therapy
guided by concentrations of amino-terminal pro–B-type natriuretic peptide (NT-proBNP) is …

Natriuretic peptide testing in heart failure

HN Kim, JL Januzzi Jr - Circulation, 2011 - Am Heart Assoc
Properly Multinational Study2 and the Pro-BNP Investigation of Dyspnea in the Emergency
Department7 showed that NP levels were more accurate for diagnosis or exclusion of ADHF …

Natriuretic peptide-guided heart failure management

R Troughton, G Michael Felker… - European heart …, 2014 - academic.oup.com
The natriuretic peptides are important tools to establish diagnosis and prognosis in heart
failure (HF). With application of therapies for HF, changes in both B-type natriuretic peptide …

Soluble concentrations of the interleukin receptor family member ST2 and β-blocker therapy in chronic heart failure

HK Gaggin, S Motiwala, A Bhardwaj… - Circulation: Heart …, 2013 - Am Heart Assoc
Background—Concentrations of soluble (s) ST2 predict prognosis in heart failure. We
recently found changing doses of β-blocker (BB) may affect sST2 concentrations. It remains …

AST/ALT ratio predicts the functional severity of chronic heart failure with reduced left ventricular ejection fraction

M Ewid, H Sherif, AS Allihimy, SA Alharbi… - BMC research …, 2020 - Springer
Objective Despite previous research that focused on liver transaminases as predictors of
cardiovascular disease, there has been limited research evaluating the predictive value of …

Serial measurement of galectin‐3 in patients with chronic heart failure: results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) study

SR Motiwala, J Szymonifka, A Belcher… - European journal of …, 2013 - Wiley Online Library
Aims Galectin‐3 is a prognostic heart failure (HF) biomarker that may mediate cardiac
fibrosis. We examined the value of serial galectin‐3 measurement for prognosis and …

Novel biomarkers in chronic heart failure

T Ahmad, M Fiuzat, GM Felker… - Nature Reviews Cardiology, 2012 - nature.com
Understanding of chronic heart failure (HF) has progressed from a syndrome of disordered
hemodynamics caused by alterations in the structure of the heart to one that involves …