Noroviruses—the state of the art, nearly fifty years after their initial discovery

LF Ludwig-Begall, A Mauroy, E Thiry - Viruses, 2021 - mdpi.com
Human noroviruses are recognised as the major global cause of viral gastroenteritis. Here,
we provide an overview of notable advances in norovirus research and provide a short …

Respiratory syncytial virus infections in adults: a narrative review

JG Wildenbeest, DM Lowe, JF Standing… - The Lancet Respiratory …, 2024 - thelancet.com
Respiratory syncytial virus (RSV), an RNA virus spread by droplet infection that affects all
ages, is increasingly recognised as an important pathogen in adults, especially among older …

Treatment of chronic or relapsing COVID-19 in immunodeficiency

LAK Brown, E Moran, A Goodman, H Baxendale… - Journal of Allergy and …, 2022 - Elsevier
Background Patients with some types of immunodeficiency can experience chronic or
relapsing infection with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) …

Norovirus: facts and reflections from past, present, and future

Y Lucero, DO Matson, S Ashkenazi, S George… - Viruses, 2021 - mdpi.com
Human Norovirus is currently the main viral cause of acute gastroenteritis (AGEs) in most
countries worldwide. Nearly 50 years after the discovery of the “Norwalk virus” by Kapikian …

Update on infections in primary antibody deficiencies

YY Demirdag, S Gupta - Frontiers in immunology, 2021 - frontiersin.org
Bacterial respiratory tract infections are the hallmark of primary antibody deficiencies
(PADs). Because they are also among the most common infections in healthy individuals …

[HTML][HTML] Favipiravir induces HuNoV viral mutagenesis and infectivity loss with clinical improvement in immunocompromised patients

AY Kreins, E Roux, J Pang, I Cheng, O Charles… - Clinical …, 2024 - Elsevier
Chronic human norovirus (HuNoV) infections in immunocompromised patients result in
severe disease, yet approved antivirals are lacking. RNA-dependent RNA polymerase …

Clinical features, immunological characteristics, and treatment outcomes of Campylobacter spp. infections in patients with common variable immunodeficiency

A Roa-Bautista, LAK Brown, S Tadros, SO Burns… - The Journal of Allergy …, 2023 - Elsevier
Background Campylobacter infection usually causes a self-limited clinical illness lasting 5 to
7 days, resolving without antimicrobial treatment in immunocompetent subjects. However …

Bowel histology of CVID patients reveals distinct patterns of mucosal inflammation

CM van Schewick, DM Lowe, SO Burns… - Journal of clinical …, 2022 - Springer
Diarrhea is the commonest gastrointestinal symptom in patients with common variable
immunodeficiency (CVID). Different pathologies in patients' bowel biopsies have been …

[HTML][HTML] Virus–host interactions between nonsecretors and human norovirus

LC Lindesmith, PD Brewer-Jensen, ML Mallory… - Cellular and Molecular …, 2020 - Elsevier
Background & Aims Human norovirus infection is the leading cause of acute gastroenteritis.
Genetic polymorphisms, mediated by the FUT2 gene (secretor enzyme), define strain …

Altered microbiota, impaired quality of life, malabsorption, infection, and inflammation in CVID patients with diarrhoea

CM Van Schewick, C Nöltner, S Abel… - Frontiers in …, 2020 - frontiersin.org
Background: Diarrhoea is the commonest gastrointestinal symptom in patients with common
variable immunodeficiency (CVID). Objective: The aim of this study was to describe the …