Oxidative stress in preeclampsia and placental diseases

R Aouache, L Biquard, D Vaiman… - International journal of …, 2018 - mdpi.com
Preeclampsia is a persistent hypertensive gestational disease characterized by high blood
pressure and proteinuria, which presents from the second trimester of pregnancy. At the …

The role of immune cells and mediators in preeclampsia

E Deer, O Herrock, N Campbell, D Cornelius… - Nature Reviews …, 2023 - nature.com
Preeclampsia is a hypertensive disorder of major concern in pregnancy than can lead to
intrauterine growth restriction, placental abruption and stillbirth. The pathophysiology of …

The role of inflammation in the pathology of preeclampsia

AC Harmon, DC Cornelius, LM Amaral… - Clinical …, 2016 - portlandpress.com
Preeclampsia (PE) affects 5–7% of all pregnancies in the United States and is the leading
cause of maternal and prenatal morbidity. PE is associated with hypertension after week 20 …

Preeclampsia: Pathophysiology and management

R Nirupama, S Divyashree, P Janhavi… - Journal of gynecology …, 2021 - Elsevier
Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered
pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset …

Oxidative stress in diabetes: implications for vascular and other complications

D Pitocco, M Tesauro, R Alessandro… - International journal of …, 2013 - mdpi.com
In recent decades, oxidative stress has become a focus of interest in most biomedical
disciplines and many types of clinical research. Increasing evidence shows that oxidative …

Inflammatory cytokines in vascular dysfunction and vascular disease

AH Sprague, RA Khalil - Biochemical pharmacology, 2009 - Elsevier
The vascular inflammatory response involves complex interaction between inflammatory
cells (neutrophils, lymphocytes, monocytes, macrophages), endothelial cells (ECs), vascular …

Evolving functions of endothelial cells in inflammation

JS Pober, WC Sessa - Nature Reviews Immunology, 2007 - nature.com
Inflammation is usually analysed from the perspective of tissue-infiltrating leukocytes.
Microvascular endothelial cells at a site of inflammation are both active participants in and …

Micro RNA‐146 represses endothelial activation by inhibiting pro‐inflammatory pathways

HS Cheng, N Sivachandran, A Lau… - EMBO molecular …, 2013 - embopress.org
Activation of inflammatory pathways in the endothelium contributes to vascular diseases,
including sepsis and atherosclerosis. We demonstrate that miR‐146a and miR‐146b are …

Linking endothelial dysfunction with endothelial cell activation

JK Liao - The Journal of clinical investigation, 2013 - Am Soc Clin Investig
The thin layer of cells that lines the interior of blood vessels, known as the endothelium,
plays a complex role in vascular biology. The endothelium mediates blood vessel tone …

Shared inflammatory pathways of rheumatoid arthritis and atherosclerotic cardiovascular disease

BN Weber, JT Giles, KP Liao - Nature Reviews Rheumatology, 2023 - nature.com
The association between chronic inflammation and increased risk of cardiovascular disease
in rheumatoid arthritis (RA) is well established. In the general population, inflammation is an …