Ferroptosis is a newly discovered type of cell death triggered by intracellular phospholipid
peroxidation that is morphologically, biologically and genetically distinct from other types of …

Flavonoids are common plant natural products able to suppress ROS-related damage and
alleviate oxidative stress. One of key mechanisms, involved in this phenomenon is chelation …

Highlights•This review briefly introduces the contributor role of ferroptosis in
stroke.•Ferroptosis inhibitors exhibit neuroprotective effects in multiple stroke models.•The …

We report the design, the synthesis and the biological evaluation of the analgesic and anti-
inflammatory activities of furoxanyl N-acylhydrazones (furoxanyl-NAH) by applying …

Ferroptosis is a regulated form of cell death, the mechanism of which is still to be
understood. 15-lipoxygenase (15LOX) complex with phosphatidylethanolamine (PE) …

Flavonoids are a subclass of phenolic compounds that occur ubiquitously in food plants and
vegetables. This class of compounds shares a common 15-carbon structure represented by …

We perform steered molecular dynamics (SMD) simulations and use the Brownian dynamics
fluctuation-dissipation-theorem (BD-FDT) to accurately compute the free-energy profiles for …

Because of its roles in human physiology, Aquaporin V (AQP5), a major intrinsic protein, has
been a subject of many in vitro studies. In particular, a 2008 experiment produced its crystal …

Abstract The European grapevine moth, Lobesia botrana (Denis & Schiffermüller), is a
serious pest in vineyards in North and South America. Mating disruption techniques have …

The use of prostaglandins and NSAIDS in the clinic has proven that lipid mediators and their
associated pathways make attractive therapeutic targets. When contemplating therapies …