Large-scale plasma proteomics comparisons through genetics and disease associations
High-throughput proteomics platforms measuring thousands of proteins in plasma combined
with genomic and phenotypic information have the power to bridge the gap between the …
with genomic and phenotypic information have the power to bridge the gap between the …
[HTML][HTML] 25 Years of translational research in the Copenhagen Prospective Studies on Asthma in Childhood (COPSAC)
The Copenhagen Prospective Studies on Asthma in Childhood (COPSAC) mother-child
cohorts have provided a foundation of 25 years of research on the origins, prevention, and …
cohorts have provided a foundation of 25 years of research on the origins, prevention, and …
[HTML][HTML] Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age
Background The upper airways present a barrier to inhaled allergens and microbes, which
alter immune responses and subsequent risk for diseases, such as allergic rhinitis (AR) …
alter immune responses and subsequent risk for diseases, such as allergic rhinitis (AR) …
Genome-wide study of early and severe childhood asthma identifies interaction between CDHR3 and GSDMB
Background Asthma with severe exacerbation is one of the most common causes of
hospitalization among young children. Exacerbations are typically triggered by respiratory …
hospitalization among young children. Exacerbations are typically triggered by respiratory …
The changes in bacterial microbiome associated with immune disorder in allergic respiratory disease
J Lyu, F Kou, X Men, Y Liu, L Tang, S Wen - Microorganisms, 2022 - mdpi.com
Allergic respiratory disease is a worldwide and increasingly prevalent health problem. Many
researchers have identified complex changes in the microbiota of the respiratory and …
researchers have identified complex changes in the microbiota of the respiratory and …
[PDF][PDF] Analysis of the expression changes of IL-17+ γδ T cells and Treg cells in bone marrow mesenchymal stem cells targeted therapy for allergic rhinitis.
B Zou, RX Zhuang, XY Sun… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: Bone marrow mesenchymal stem cells (BMSCs) have immunomodulatory and
therapeutic effects on immune system diseases. This study intends to assess the regulatory …
therapeutic effects on immune system diseases. This study intends to assess the regulatory …
Dust mite component Analysis: Identifying key allergens components for effective immunotherapy in allergic rhinitis
J Huang, R Xiang, L Tan, Y Deng, Z Tao… - International …, 2023 - Elsevier
Background The aim of this study was to examine the frequency of sensitization to house
dust mite (HDM) components among allergic rhinitis patients receiving subcutaneous …
dust mite (HDM) components among allergic rhinitis patients receiving subcutaneous …
Bilirubin metabolism in early life and respiratory health during preschool age: A combined analysis of two independent birth cohorts
Background Bilirubin has antioxidant properties, and elevated levels within the normal
range have been associated with improved lung function and decreased risk of asthma in …
range have been associated with improved lung function and decreased risk of asthma in …
Clinical significance of T helper-1/T helper-2 cytokines in peripheral blood of children with otitis media with effusion and allergic rhinitis
L Yu, J Bi, B Xu, B Yu, Y Fu - International Journal of Pediatric …, 2024 - Elsevier
Objective Otitis media with effusion (OME) is a prevalent and costly disease, especially in
children. This article analyzed the expression patterns and clinical significance of T helper-1 …
children. This article analyzed the expression patterns and clinical significance of T helper-1 …
Allergen alters IL‐2/αIL‐2‐based Treg expansion but not tolerance induction in an allergen‐specific mouse model
C Köhler, U Smole, B Kratzer, D Trapin… - Allergy, 2020 - Wiley Online Library
Abstract Background Regulatory T lymphocytes (Treg) play an important role in preventing
allergic diseases. We characterized Treg expansion kinetics, marker profiles, and …
allergic diseases. We characterized Treg expansion kinetics, marker profiles, and …