Introduction: Gene therapy is a breakthrough medical field which focuses on the therapeutic
delivery of recombinant nucleic acids in order to treat or prevent a broad spectrum of …

Influenza is an important research subject around the world because of its threat to
humanity. Influenza A virus (IAV) causes seasonal epidemics and sporadic, but dangerous …

There are many reports about the interaction of multilayer capsules with biological systems
in the literature. A majority of them are devoted to the in vitro study with two-dimensional cell …

Growth factor incorporation in biomedical constructs for their local delivery enables specific
pharmacological effects such as the induction of cell growth and differentiation. This has …

While DNA and messenger RNA (mRNA) based therapies are currently changing the
biomedical field, the delivery of genetic materials remains the key problem preventing the …

Histone deacetylase 6 (HDAC6), through the repertoire of its substrate proteins, plays a
critical role in human physiology, and an aberrant function of HDAC6 contributes to various …

Emerging therapies based on localized delivery of siRNA to lungs have opened up exciting
possibilities for treatment of different lung diseases. Localized delivery of siRNA to lungs has …

Optogenetic prosthetics is an approach to restore visual function in retinal degenerative
diseases. It implies the delivery of genes encoding light-sensitive proteins to retinal cells that …

Human respiratory syncytial virus (HRSV) infection is a common cause of severe lower
respiratory tract diseases such as bronchiolitis and pneumonia. Both virus replication and …

The primary objective of this review is to describe the various mechanisms of RNA
interference (RNAi) suppression in emerging RNA viruses. A search was conducted using …