Abstract Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many
human disorders. The persistence of these viral genomes in all malignant cells, yet with the …

During the generation of a successful adaptive immune response, multiple molecular
signals are required. A primary signal is the binding of cognate antigen to an antigen …

Abstract The Cancer Genome Atlas profiled 279 head and neck squamous cell carcinomas
(HNSCCs) to provide a comprehensive landscape of somatic genomic alterations. Here we …

EBV was the first human virus to be directly implicated in carcinogenesis. It infects> 90% of
the world's population. Although most humans coexist with the virus without serious …

Over the last two decades, it has been recognized that head and neck cancers, primarily in
the oropharynx, can be a distinct entity that is causally related to human papilloma virus …

Epstein–Barr virus (EBV) was the first human virus found to encode microRNAs (miRNAs),
but the function of these miRNAs has been obscure. Nasopharyngeal carcinoma (NPC) is …

Head and neck cancer is the fifth most common cancer worldwide. It is often amenable to
curative intent therapy when localized to the head and neck region, but it carries a poor …

The Epstein‐Barr virus (EBV) is a herpes virus which establishes a life‐long persistent
infection in over 90% of the human adult population world‐wide. Based on its association …

The oncogenic Epstein–Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) has
structural features and functions reminiscent of a constitutively active TNF family receptor …

Oncolytic adenovirus is an attractive platform for immunotherapy because virus replication is
highly immunogenic and not subject to tolerance. Although oncolysis releases tumor …