Resting-state functional MR imaging: a new window to the brain

F Barkhof, S Haller, SARB Rombouts - Radiology, 2014 - pubs.rsna.org
Resting-state (RS) functional magnetic resonance (MR) imaging constitutes a novel
paradigm that examines spontaneous brain function by using blood oxygen level …

Mind the gap: from neurons to networks to outcomes in multiple sclerosis

DT Chard, AAS Alahmadi, B Audoin… - Nature Reviews …, 2021 - nature.com
MRI studies have provided valuable insights into the structure and function of neural
networks, particularly in health and in classical neurodegenerative conditions such as …

Hyperconnectivity is a fundamental response to neurological disruption.

FG Hillary, CA Roman, U Venkatesan… - …, 2015 - psycnet.apa.org
Objective: In the cognitive and clinical neurosciences, the past decade has been marked by
dramatic growth in a literature examining brain “connectivity” using noninvasive methods …

Reconciling abnormalities of brain network structure and function in schizophrenia

A Fornito, ET Bullmore - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Schizophrenia patients often show reduced structural connectivity.•Despite this,
increased functional connectivity is a common finding.•Structure–function decoupling may …

[HTML][HTML] Functional connectivity in multiple sclerosis: recent findings and future directions

M Tahedl, SM Levine, MW Greenlee, R Weissert… - Frontiers in …, 2018 - frontiersin.org
Multiple sclerosis is a debilitating disorder resulting from scattered lesions in the central
nervous system. Because of the high variability of the lesion patterns between patients, it is …

Gray matter damage in multiple sclerosis: impact on clinical symptoms

CEP Van Munster, LE Jonkman, HC Weinstein… - Neuroscience, 2015 - Elsevier
Traditionally, multiple sclerosis (MS) is considered to be a disease primarily affecting the
white matter (WM). However, the development of some clinical symptoms such as cognitive …

Depletion of brain functional connectivity enhancement leads to disability progression in multiple sclerosis: a longitudinal resting-state fMRI study

A Faivre, E Robinet, M Guye… - Multiple Sclerosis …, 2016 - journals.sagepub.com
Background: The compensatory effect of brain functional connectivity enhancement in
relapsing-remitting multiple sclerosis (RRMS) remains controversial. Objective: To …

[HTML][HTML] Cognitive and clinical dysfunction, altered MEG resting-state networks and thalamic atrophy in multiple sclerosis

P Tewarie, MM Schoonheim, CJ Stam… - PloS one, 2013 - journals.plos.org
The relation between pathological findings and clinical and cognitive decline in Multiple
Sclerosis remains unclear. Here, we tested the hypothesis that altered functional …

Default mode network changes in multiple sclerosis: a link between depression and cognitive impairment?

S Bonavita, R Sacco, S Esposito… - European journal of …, 2017 - Wiley Online Library
Background and purpose In multiple sclerosis (MS), depression is a common disorder
whose pathophysiology is still debated. To gain insights into the pathophysiology of …

Altered nuclei-specific thalamic functional connectivity patterns in multiple sclerosis and their associations with fatigue and cognition

F Lin, R Zivadinov, J Hagemeier… - Multiple Sclerosis …, 2019 - journals.sagepub.com
Background: The thalamus, affected early in multiple sclerosis (MS), is a heterogeneous
composition of functionally distinct nuclei and is associated with fatigue, cognition, and other …