Roles of transposable elements in the regulation of mammalian transcription

R Fueyo, J Judd, C Feschotte, J Wysocka - Nature reviews Molecular …, 2022 - nature.com
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …

[HTML][HTML] Transposable elements as essential elements in the control of gene expression

A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …

[HTML][HTML] Role of transposable elements in genome stability: implications for health and disease

A Bhat, T Ghatage, S Bhan, GP Lahane, A Dhar… - International journal of …, 2022 - mdpi.com
Most living organisms have in their genome a sizable proportion of DNA sequences capable
of mobilization; these sequences are commonly referred to as transposons, transposable …

Transposable elements in plants: Recent advancements, tools and prospects

M Ramakrishnan, L Satish, A Sharma… - Plant Molecular Biology …, 2022 - Springer
Transposable elements (TEs) have long been considered junk DNA; however, the
availability of genome sequences and the growth of omics databases have accelerated the …

Regulation and function of R-loops at repetitive elements

A Gambelli, A Ferrando, C Boncristiani, S Schoeftner - Biochimie, 2023 - Elsevier
R-loops are atypical, three-stranded nucleic acid structures that contain a stretch of RNA:
DNA hybrids and an unpaired, single stranded DNA loop. R-loops are physiological relevant …

[HTML][HTML] The talented LncRNAs: meshing into transcriptional regulatory networks in cancer

D Segal, J Dostie - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) are a large class of RNA molecules
known to regulate the expression of genes. Although expressed in a highly tissue-specific …

[HTML][HTML] CRISPR/Cas9-mediated LINC00511 knockout strategies, increased apoptosis of breast cancer cells via suppressing antiapoptotic genes

N Azadbakht, A Doosti, MS Jami - Biological procedures online, 2022 - Springer
Background The growing detection of long noncoding RNAs (lncRNAs) required the
application of functional approaches in order to provide absolutely precise, conducive, and …

[HTML][HTML] Genomic analyses of non-coding RNAs overlapping transposable elements and its implication to human diseases

EG Park, H Ha, DH Lee, WR Kim, YJ Lee… - International journal of …, 2022 - mdpi.com
It is estimated that up to 80% of the human genome is transcribed into RNA molecules but
less than 2% of the genome encodes the proteins, and the rest of the RNA transcripts that …

[HTML][HTML] The evolutionary volte-face of transposable elements: from harmful jumping genes to major drivers of genetic innovation

M Nicolau, N Picault, G Moissiard - Cells, 2021 - mdpi.com
Transposable elements (TEs) are self-replicating DNA elements that constitute major
fractions of eukaryote genomes. Their ability to transpose can modify the genome structure …

[HTML][HTML] Promising predictive molecular biomarkers for cervical cancer

M Lizano, A Carrillo-García… - International …, 2024 - spandidos-publications.com
Cervical cancer (CC) constitutes a serious public health problem. Vaccination and screening
programs have notably reduced the incidence of CC worldwide by> 80%; however, the …