Roles of transposable elements in the regulation of mammalian transcription
Transposable elements (TEs) comprise about half of the mammalian genome. TEs often
contain sequences capable of recruiting the host transcription machinery, which they use to …
contain sequences capable of recruiting the host transcription machinery, which they use to …
[HTML][HTML] Transposable elements as essential elements in the control of gene expression
A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …
[HTML][HTML] Role of transposable elements in genome stability: implications for health and disease
Most living organisms have in their genome a sizable proportion of DNA sequences capable
of mobilization; these sequences are commonly referred to as transposons, transposable …
of mobilization; these sequences are commonly referred to as transposons, transposable …
Transposable elements in plants: Recent advancements, tools and prospects
Transposable elements (TEs) have long been considered junk DNA; however, the
availability of genome sequences and the growth of omics databases have accelerated the …
availability of genome sequences and the growth of omics databases have accelerated the …
Regulation and function of R-loops at repetitive elements
A Gambelli, A Ferrando, C Boncristiani, S Schoeftner - Biochimie, 2023 - Elsevier
R-loops are atypical, three-stranded nucleic acid structures that contain a stretch of RNA:
DNA hybrids and an unpaired, single stranded DNA loop. R-loops are physiological relevant …
DNA hybrids and an unpaired, single stranded DNA loop. R-loops are physiological relevant …
[HTML][HTML] The talented LncRNAs: meshing into transcriptional regulatory networks in cancer
D Segal, J Dostie - Cancers, 2023 - mdpi.com
Simple Summary Long non-coding RNAs (lncRNAs) are a large class of RNA molecules
known to regulate the expression of genes. Although expressed in a highly tissue-specific …
known to regulate the expression of genes. Although expressed in a highly tissue-specific …
[HTML][HTML] CRISPR/Cas9-mediated LINC00511 knockout strategies, increased apoptosis of breast cancer cells via suppressing antiapoptotic genes
N Azadbakht, A Doosti, MS Jami - Biological procedures online, 2022 - Springer
Background The growing detection of long noncoding RNAs (lncRNAs) required the
application of functional approaches in order to provide absolutely precise, conducive, and …
application of functional approaches in order to provide absolutely precise, conducive, and …
[HTML][HTML] Genomic analyses of non-coding RNAs overlapping transposable elements and its implication to human diseases
EG Park, H Ha, DH Lee, WR Kim, YJ Lee… - International journal of …, 2022 - mdpi.com
It is estimated that up to 80% of the human genome is transcribed into RNA molecules but
less than 2% of the genome encodes the proteins, and the rest of the RNA transcripts that …
less than 2% of the genome encodes the proteins, and the rest of the RNA transcripts that …
[HTML][HTML] The evolutionary volte-face of transposable elements: from harmful jumping genes to major drivers of genetic innovation
Transposable elements (TEs) are self-replicating DNA elements that constitute major
fractions of eukaryote genomes. Their ability to transpose can modify the genome structure …
fractions of eukaryote genomes. Their ability to transpose can modify the genome structure …
[HTML][HTML] Promising predictive molecular biomarkers for cervical cancer
M Lizano, A Carrillo-García… - International …, 2024 - spandidos-publications.com
Cervical cancer (CC) constitutes a serious public health problem. Vaccination and screening
programs have notably reduced the incidence of CC worldwide by> 80%; however, the …
programs have notably reduced the incidence of CC worldwide by> 80%; however, the …