Importance The treatment landscape of metastatic renal cell carcinoma has evolved rapidly
over the last decade. Recent combination approaches heralded by targeting immune …

Muscle invasive bladder cancer (MIBC) is a widespread malignancy with a worse prognosis
often related to a late diagnosis. For early-stage MIBC pts, a multidisciplinary approach is …

Methods Patients with previously untreated advanced/metastatic nccRCC, Karnofsky
performance status≥ 70%, and any International Metastatic Renal Cell Carcinoma …

Anti-VEGF (vascular endothelial growth factor) agents were associated with increased risk of
several cardiovascular events, while one meta-analysis did not show any significantly …

As a type of regulated cell death induced by Ras selective lethal (RSL) compounds such as
erasti, ferroptosis is characterized by iron-dependent lipid peroxide accumulation to lethal …

The past 30 years have borne witness to a gradual evolution in the treatment landscape of
advanced renal cell carcinoma (aRCC). Early immunotherapy approaches such as …

Background Kidney Renal Clear Cell Carcinoma (KIRC) is one of the most prevalent types
of cancer worldwide. KIRC has a poor prognosis and, to date, immunotherapy based on …

Background Both docetaxel and androgen-receptor-axis-targeted (ARAT) agents are
approved in metastatic castration-sensitive prostate cancer (mCSPC) patients. Predictive …

Background: Ferroptosis is a potential target for cancer therapy, and lncRNAs can also affect
ferroptosis by regulating related genes. The pathogenesis of clear cell renal cell carcinoma …

Our network meta-analysis demonstrates that sRCC are responsive to immune-based
combinations. The dual ICI with nivolumab plus ipilimumab improved all efficacy outcomes …