The noncanonical inflammasome-induced pyroptosis and septic shock
Sepsis remains one of the most common and lethal conditions globally. Currently, no
proposed target specific to sepsis improves survival in clinical trials. Thus, an in-depth …
proposed target specific to sepsis improves survival in clinical trials. Thus, an in-depth …
[HTML][HTML] Engineering materials for pyroptosis induction in cancer treatment
J Liu, T Chen, XL Liu, ZH Li, Y Zhang - Bioactive Materials, 2024 - Elsevier
Cancer remains a significant global health concern, necessitating the development of
innovative therapeutic strategies. This research paper aims to investigate the role of …
innovative therapeutic strategies. This research paper aims to investigate the role of …
Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy
R Freitas, E Ferreira, A Miranda, D Ferreira… - ACS …, 2024 - ACS Publications
Advanced-stage solid primary tumors and metastases often express mucin 16 (MUC16),
carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not …
carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not …
Biomimetic Platelet‐Cloaked Nanoparticles for the Delivery of Anti‐Inflammatory Curcumin in the Treatment of Atherosclerosis
F Fontana, G Molinaro, S Moroni… - Advanced …, 2024 - Wiley Online Library
Atherosclerosis still represents a major driver of cardiovascular diseases worldwide.
Together with accumulation of lipids in the plaque, inflammation is recognized as one of the …
Together with accumulation of lipids in the plaque, inflammation is recognized as one of the …
Preparation of Compound Salvia miltiorrhiza–Blumea balsamifera Nanoemulsion Gel and Its Effect on Hypertrophic Scars in the Rabbit Ear Model
T Chen, Z Wang, X Gong, J Zhang… - Molecular …, 2024 - ACS Publications
Hypertrophic scars (HS) still remain an urgent challenge in the medical community.
Traditional Chinese medicine (TCM) has unique advantages in the treatment of HS …
Traditional Chinese medicine (TCM) has unique advantages in the treatment of HS …
Apoptosis‐Sensitizing Tumor Nanomedicine by Regulating Pyroptosis‐Associated Inflammatory Cell Death
F Du, H Zhao, Y Song, Z Feng, K Liu… - Advanced Functional …, 2024 - Wiley Online Library
The vigorous development of cancer nanomedicine has revolutionized traditional oncology
medicine, but it is also limited by the continuous mutation of cunning cancer cells, leading to …
medicine, but it is also limited by the continuous mutation of cunning cancer cells, leading to …
[HTML][HTML] A systematic review of microplastics emissions in kitchens: Understanding the links with diseases in daily life
Y Liu, Y Cao, H Li, H Liu, L Bi, Q Chen, R Peng - Environment International, 2024 - Elsevier
The intensification of microplastics (MPs) pollution has emerged as a formidable
environmental challenge, with profound global implications. The pervasive presence of MPs …
environmental challenge, with profound global implications. The pervasive presence of MPs …
[HTML][HTML] An Evaluation of Urease A Subunit Nanocapsules as a Vaccine in a Mouse Model of Helicobacter pylori Infection
I Skakic, JE Francis, C Dekiwadia, I Aibinu, M Huq… - Vaccines, 2023 - mdpi.com
Using removable silica templates, protein nanocapsules comprising the A subunit of
Helicobacter pylori urease (UreA) were synthesised. The templates were of two sizes, with …
Helicobacter pylori urease (UreA) were synthesised. The templates were of two sizes, with …
Vaccine adjuvants: Tailoring innate recognition to send the right message
EC Lavelle, CP McEntee - Immunity, 2024 - cell.com
Adjuvants play pivotal roles in vaccine development, enhancing immunization efficacy
through prolonged retention and sustained release of antigen, lymph node targeting, and …
through prolonged retention and sustained release of antigen, lymph node targeting, and …
Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function
TM Legroux, HS Schymik, G Gasparoni… - Frontiers in …, 2024 - frontiersin.org
Glucocorticoids, which have long served as fundamental therapeutics for diverse
inflammatory conditions, are still widely used, despite associated side effects limiting their …
inflammatory conditions, are still widely used, despite associated side effects limiting their …