The noncanonical inflammasome-induced pyroptosis and septic shock

J Wu, J Cai, Y Tang, B Lu - Seminars in Immunology, 2023 - Elsevier
Sepsis remains one of the most common and lethal conditions globally. Currently, no
proposed target specific to sepsis improves survival in clinical trials. Thus, an in-depth …

[HTML][HTML] Engineering materials for pyroptosis induction in cancer treatment

J Liu, T Chen, XL Liu, ZH Li, Y Zhang - Bioactive Materials, 2024 - Elsevier
Cancer remains a significant global health concern, necessitating the development of
innovative therapeutic strategies. This research paper aims to investigate the role of …

Targeted and Self-Adjuvated Nanoglycovaccine Candidate for Cancer Immunotherapy

R Freitas, E Ferreira, A Miranda, D Ferreira… - ACS …, 2024 - ACS Publications
Advanced-stage solid primary tumors and metastases often express mucin 16 (MUC16),
carrying immature glycans such as the Tn antigen, resulting in specific glycoproteoforms not …

Biomimetic Platelet‐Cloaked Nanoparticles for the Delivery of Anti‐Inflammatory Curcumin in the Treatment of Atherosclerosis

F Fontana, G Molinaro, S Moroni… - Advanced …, 2024 - Wiley Online Library
Atherosclerosis still represents a major driver of cardiovascular diseases worldwide.
Together with accumulation of lipids in the plaque, inflammation is recognized as one of the …

Preparation of Compound Salvia miltiorrhizaBlumea balsamifera Nanoemulsion Gel and Its Effect on Hypertrophic Scars in the Rabbit Ear Model

T Chen, Z Wang, X Gong, J Zhang… - Molecular …, 2024 - ACS Publications
Hypertrophic scars (HS) still remain an urgent challenge in the medical community.
Traditional Chinese medicine (TCM) has unique advantages in the treatment of HS …

Apoptosis‐Sensitizing Tumor Nanomedicine by Regulating Pyroptosis‐Associated Inflammatory Cell Death

F Du, H Zhao, Y Song, Z Feng, K Liu… - Advanced Functional …, 2024 - Wiley Online Library
The vigorous development of cancer nanomedicine has revolutionized traditional oncology
medicine, but it is also limited by the continuous mutation of cunning cancer cells, leading to …

[HTML][HTML] A systematic review of microplastics emissions in kitchens: Understanding the links with diseases in daily life

Y Liu, Y Cao, H Li, H Liu, L Bi, Q Chen, R Peng - Environment International, 2024 - Elsevier
The intensification of microplastics (MPs) pollution has emerged as a formidable
environmental challenge, with profound global implications. The pervasive presence of MPs …

[HTML][HTML] An Evaluation of Urease A Subunit Nanocapsules as a Vaccine in a Mouse Model of Helicobacter pylori Infection

I Skakic, JE Francis, C Dekiwadia, I Aibinu, M Huq… - Vaccines, 2023 - mdpi.com
Using removable silica templates, protein nanocapsules comprising the A subunit of
Helicobacter pylori urease (UreA) were synthesised. The templates were of two sizes, with …

Vaccine adjuvants: Tailoring innate recognition to send the right message

EC Lavelle, CP McEntee - Immunity, 2024 - cell.com
Adjuvants play pivotal roles in vaccine development, enhancing immunization efficacy
through prolonged retention and sustained release of antigen, lymph node targeting, and …

Immunomodulation by glucocorticoid-induced leucine zipper in macrophages: enhanced phagocytosis, protection from pyroptosis, and altered mitochondrial function

TM Legroux, HS Schymik, G Gasparoni… - Frontiers in …, 2024 - frontiersin.org
Glucocorticoids, which have long served as fundamental therapeutics for diverse
inflammatory conditions, are still widely used, despite associated side effects limiting their …