Hydatidiform moles are intriguing pathologic entities representing abnormal placental villous
tissue with unique genetic profiles and a wide spectrum of morphologic features, which …

Prior to zygotic genome activation, early mammalian development relies on maternal-effect
genes to orchestrate the oocyte-to-embryo transition. Recently, a subcortical maternal …

Androgenetic complete hydatidiform moles are human pregnancies with no embryos and
affect 1 in every 1,400 pregnancies. They have mostly androgenetic monospermic genomes …

STUDY QUESTION What is the risk of further molar pregnancies for women with one or
more hydatidiform moles (HM) in relation to molar subtype. SUMMARY ANSWER Women …

Hydatidiform mole (HM) is an abnormal human pregnancy characterized by excessive
growth of placental trophoblasts and abnormal early embryonic development. Following a …

STUDY QUESTION Are mutations in NLRP2/7 (NACHT, LRR and PYD domains-containing
protein 2/7) or KHDC3L (KH Domain Containing 3 Like) associated with recurrent …

Hydatidiform mole (HM) is an aberrant human pregnancy with abnormal embryonic
development and excessive proliferation of the trophoblast. Recessive mutations in NLRP7 …

The essential contribution of multiple maternal factors to early mammalian development is
rapidly altering the view that mammals have a unique pattern of development compared to …

The placenta is a crucial organ for supporting a healthy pregnancy, and defective
development or function of the placenta is implicated in a number of complications of …

Background In a subset of imprinting disorders caused by epimutations, multiple imprinted
loci are affected. Familial occurrence of multilocus imprinting disorders is rare …