Opportunities and challenges for immunosuppression in the context of pig-to-human xenotransplantation

G Onyeaghala, CR Dorr, AK Israni - Med, 2024 - cell.com
The transplantation of organ (s) across species may alleviate the shortage of available
donor kidneys for an ever-growing number of patients on transplant waiting lists. However …

Extreme phenotype sampling and next generation sequencing to identify genetic variants associated with tacrolimus in African American kidney transplant recipients

ME Mohamed, B Guo, B Wu, DP Schladt… - The …, 2024 - nature.com
African American (AA) kidney transplant recipients (KTRs) have poor outcomes, which may
in-part be due to tacrolimus (TAC) sub-optimal immunosuppression. We previously …

[HTML][HTML] Pharmacomicrobiomics–Another frontier of precision medicine

S Chenchula, S Atal, A Bhattacharyya… - Indian Journal of …, 2024 - journals.lww.com
The burgeoning field of pharmacogenomics has emerged as a promising frontier in the
quest for precision medicine.[1] Pharmacogenomics has focused primarily on genetic …

Extreme Phenotype Sampling and Next Generation Sequencing to Identify Genetic Variants Associated with Tacrolimus in African American Kidney Transplant …

C Dorr, M Mohamed, B Guo, B Wu, D Schladt… - 2024 - researchsquare.com
African American (AA) kidney transplant recipients (KTRs) have poor outcomes, which may
in-part be due to tacrolimus (TAC) sub-optimal immunosuppression. We previously …