[HTML][HTML] Anti-cancer potential of cannabinoids, terpenes, and flavonoids present in cannabis

AM Tomko, EG Whynot, LD Ellis, DJ Dupré - Cancers, 2020 - mdpi.com
In recent years, and even more since its legalization in several jurisdictions, cannabis and
the endocannabinoid system have received an increasing amount of interest related to their …

[HTML][HTML] Synergistic effects of natural compounds and conventional chemotherapeutic agents: Recent insights for the development of cancer treatment strategies

AM Castañeda, CM Meléndez, D Uribe… - Heliyon, 2022 - cell.com
Cancer is one of the leading causes of death in the world. Chemotherapy is presented as an
option for treatment of this disease, however, low specificity, high resistance rates, toxicity …

[HTML][HTML] Baicalein as promising anticancer agent: A comprehensive analysis on molecular mechanisms and therapeutic perspectives

AKMH Morshed, S Paul, A Hossain, T Basak… - Cancers, 2023 - mdpi.com
Simple Summary Cancer is a multifactorial disease characterized by excessive cell
proliferation in a specific organ. The most common treatments include chemotherapy …

Natural borneol sensitizes human glioma cells to cisplatin-induced apoptosis by triggering ROS-mediated oxidative damage and regulation of MAPKs and PI3K/AKT …

W Cao, X Zhai, J Ma, X Fu, B Zhao, P Zhang… - Pharmaceutical …, 2020 - Taylor & Francis
Context Cisplatin-based chemotherapy was widely used in treating human malignancies.
However, side effects and chemoresistance remains the major obstacle. Objective To verify …

Baicalein, as a prooxidant, triggers mitochondrial apoptosis in MCF-7 human breast cancer cells through mobilization of intracellular copper and reactive oxygen …

ZH Liu, CX Yang, L Zhang, CY Yang… - OncoTargets and …, 2019 - Taylor & Francis
Background Baicalein, a natural flavonoid derived from traditional Chinese herb Scutellaria
baicalensis Georg (known as Huang Qin in Chinese), has been reported to exhibit notable …

[HTML][HTML] Gather wisdom to overcome barriers: well-designed nano-drug delivery systems for treating gliomas

J Cui, Y Xu, H Tu, H Zhao, H Wang, L Di… - … Pharmaceutica Sinica B, 2022 - Elsevier
Due to the special physiological and pathological characteristics of gliomas, most
therapeutic drugs are prevented from entering the brain. To improve the poor prognosis of …

[HTML][HTML] Enhanced anticancer efficiency of doxorubicin against human glioma by natural borneol through triggering ROS-mediated signal

W Cao, Y Li, Y Hou, M Yang, X Fu, B Zhao… - Biomedicine & …, 2019 - Elsevier
Doxorubicin (DOX) as a first-line chemotherapeutic drug has been widely used for therapy of
human cancers. However, side effects and chemo-resistance severely blocked its clinic …

[HTML][HTML] Norbornene and related structures as scaffolds in the search for new cancer treatments

G Calvo-Martín, D Plano, N Martínez-Sáez, C Aydillo… - Pharmaceuticals, 2022 - mdpi.com
The norbornene scaffold has arisen as a promising structure in medicinal chemistry due to
its possible therapeutic application in cancer treatment. The development of norbornene …

[HTML][HTML] Chemical composition and biological activities of essential oils from six lamiaceae folk medicinal plants

J Sun, P Sun, C Kang, L Zhang, L Guo… - Frontiers in Plant …, 2022 - frontiersin.org
Essential oils have attracted wide attention in recent years due to their extensive
applications in natural functional ingredients, pharmaceutical preparations, biomedical …

Analgesic and anti-inflammatory effects and mechanism of action of borneol on photodynamic therapy of acne

J Ji, R Zhang, H Li, J Zhu, Y Pan, Q Guo - Environmental Toxicology and …, 2020 - Elsevier
This study aims to explore the analgesic and anti-inflammatory effects of borneol, a
traditional Chinese medicine, on photodynamic treatment of acne. Here, we found that …