[HTML][HTML] Role of HSP90 in Cancer
B Birbo, EE Madu, CO Madu, A Jain, Y Lu - International journal of …, 2021 - mdpi.com
HSP90 is a vital chaperone protein conserved across all organisms. As a chaperone protein,
it correctly folds client proteins. Structurally, this protein is a dimer with monomer subunits …
it correctly folds client proteins. Structurally, this protein is a dimer with monomer subunits …
Precision medicine in breast cancer
TG Odle - Radiologic technology, 2017 - Am Soc Radiol Tech
Breast cancer care has improved markedly in recent decades, but new advancements in
diagnosis and treatment depend on translating genomics and precision medicine into …
diagnosis and treatment depend on translating genomics and precision medicine into …
[HTML][HTML] The dual effect of morphine on tumor development
H Tuerxun, J Cui - Clinical and Translational Oncology, 2019 - Springer
Morphine is a classic opioid drug used for reducing pain and is commonly prescribed as an
effective drug to control cancer pain. Morphine has a direct role in the central nervous …
effective drug to control cancer pain. Morphine has a direct role in the central nervous …
[HTML][HTML] Collagen-I influences the post-translational regulation, binding partners and role of Annexin A2 in breast cancer progression
Introduction The extracellular matrix (ECM) has been heavily implicated in the development
and progression of cancer. We have previously shown that Annexin A2 is integral in the …
and progression of cancer. We have previously shown that Annexin A2 is integral in the …
A network analysis to identify pathophysiological pathways distinguishing ischaemic from non‐ischaemic heart failure
IE Sama, RJ Woolley, JF Nauta… - European Journal of …, 2020 - Wiley Online Library
Aims Heart failure (HF) is frequently caused by an ischaemic event (eg myocardial
infarction) but might also be caused by a primary disease of the myocardium …
infarction) but might also be caused by a primary disease of the myocardium …
Elevated mRNA level of Y-box binding protein 1 indicates unfavorable prognosis correlated with macrophage infiltration and T cell exhaustion in luminal breast cancer
Z Lv, C Xue, L Zhang, J Sun, C Bo - Cancer Management and …, 2021 - Taylor & Francis
Purpose The Y-box binding protein 1 (YBX1) gene encodes the multifunctional protein YB1
that is associated with the dysregulation of numerous cancer-related genes. However, the …
that is associated with the dysregulation of numerous cancer-related genes. However, the …
[HTML][HTML] Association of uPA and PAI-1 tumor levels and 4G/5G variants of PAI-1 gene with disease outcome in luminal HER2-negative node-negative breast cancer …
M Jevrić, IZ Matić, A Krivokuća, M Đorđić Crnogorac… - BMC cancer, 2019 - Springer
Background The aim of this study was to evaluate the prognostic potential of urokinase-type
plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) tumor tissue …
plasminogen activator (uPA) and plasminogen activator inhibitor type 1 (PAI-1) tumor tissue …
[HTML][HTML] Plasminogen activator inhibitor 1 promotes immunosuppression in human non-small cell lung cancers by enhancing TGF-Β1 expression in macrophage
C Zhu, H Shen, L Zhu, F Zhao, Y Shu - Cellular Physiology and …, 2018 - karger.com
Background: Plasminogen activator inhibitor-1 (PAI-1) has been regarded as a risk factor for
thrombosis and atherosclerosis. Since it has been shown that PAI-1 can activate …
thrombosis and atherosclerosis. Since it has been shown that PAI-1 can activate …
Prediction of therapy response in ovarian cancer: where are we now?
Therapy resistance is a major challenge in the management of ovarian cancer (OC).
Advances in detection and new technology validation have led to the emergence of …
Advances in detection and new technology validation have led to the emergence of …
Proteomics analysis of human breast milk by two‐dimensional polyacrylamide gel electrophoresis (2D‐PAGE) coupled with mass spectrometry to assess breast …
Breast cancer (BC) is one of the most common cancers and one of the most common causes
for cancer‐related mortality. Discovery of protein biomarkers associated with cancer is …
for cancer‐related mortality. Discovery of protein biomarkers associated with cancer is …