The influence of microbiota on ferroptosis in intestinal diseases
T Yao, L Li - Gut Microbes, 2023 - Taylor & Francis
Ferroptosis is a distinctive form of iron-dependent necrotic cell death, characterized by
excessive lipid peroxidation on cellular membranes and compromised cellular antioxidant …
excessive lipid peroxidation on cellular membranes and compromised cellular antioxidant …
[HTML][HTML] The Gum–Gut Axis: Periodontitis and the Risk of Gastrointestinal Cancers
Simple Summary Periodontitis, a chronic inflammatory disease of the gums, and the oral
microbiome have been recently implicated in the development of various cancers. Due to …
microbiome have been recently implicated in the development of various cancers. Due to …
[HTML][HTML] Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics
JB Simpson, ME Walker, JJ Sekela, SM Ivey… - Cell Host & Microbe, 2024 - cell.com
Hormones and neurotransmitters are essential to homeostasis, and their disruptions are
connected to diseases ranging from cancer to anxiety. The differential reactivation of …
connected to diseases ranging from cancer to anxiety. The differential reactivation of …
[HTML][HTML] Irinotecan cause the side effects on development and adult physiology, and induces intestinal damage via innate immune response and oxidative damage in …
J He, S Han, Y Wang, Q Kang, X Wang, Y Su… - Biomedicine & …, 2023 - Elsevier
Chemotherapy leads to significant side effects in patients, especially in the gut, resulting in
various clinical manifestations and enhanced economic pressure. Until now, many of the …
various clinical manifestations and enhanced economic pressure. Until now, many of the …
Gut microbiota in cancer: insights on microbial metabolites and therapeutic strategies
Y Chen, X Wang, Y Ye, Q Ren - Medical Oncology, 2023 - Springer
In recent years, the role of gut microbiota in cancer treatment has attracted substantial
attention. It is now well established that gut microbiota and its metabolites significantly …
attention. It is now well established that gut microbiota and its metabolites significantly …
[HTML][HTML] Comprehensive analyses identify potential biomarkers for encephalitis in HIV infection
S Wang, X Ding, Z Li, F Rao, H Xu, J Lu, X Ma… - Scientific Reports, 2023 - nature.com
Human immunodeficiency virus encephalitis (HIVE) is a severe neurological complication
after HIV infection. Evidence shows that genetic factors play an important role in HIVE. The …
after HIV infection. Evidence shows that genetic factors play an important role in HIVE. The …
[HTML][HTML] Unraveling the role of medicinal plants and Gut microbiota in colon cancer: Towards microbiota-based strategies for prevention and treatment
Colon cancer remains one of the leading causes of morbidity and mortality worldwide. Given
its widespread prevalence, the identification of new anticancer drugs is crucial. Medicinal …
its widespread prevalence, the identification of new anticancer drugs is crucial. Medicinal …
Ginsenoside Rh4 alleviates gastrointestinal mucositis and enhances chemotherapy efficacy through modulating gut microbiota
X Bai, J Deng, Z Duan, R Fu, C Zhu, D Fan - Phytomedicine, 2024 - Elsevier
Background Gastrointestinal mucositis stands as one of the most severe side effects of
irinotecan (CPT-11). however, only palliative treatment is available at present. Therefore …
irinotecan (CPT-11). however, only palliative treatment is available at present. Therefore …
Discovery of a botanical compound as a broad-spectrum inhibitor against gut microbial β-glucuronidases from the Tibetan medicine Rhodiola crenulata
L Chen, XD Hou, GH Zhu, J Huang, ZB Guo… - International Journal of …, 2024 - Elsevier
Gut microbial β-glucuronidases (gmβ-GUS) played crucial roles in regulating a variety of
endogenous substances and xenobiotics on the circulating level, thus had been recognized …
endogenous substances and xenobiotics on the circulating level, thus had been recognized …
Gut Microbiota—Adversary or Ally? Its Role and Significance in Colorectal Cancer Pathogenesis, Progression, and Treatment
K Chawrylak, M Leśniewska, K Mielniczek, K Sędłak… - Cancers, 2024 - mdpi.com
In 2022, colorectal cancer (CRC) was the third most prevalent malignancy worldwide. The
therapeutic approach for CRC typically involves a multimodal regimen. The human gut …
therapeutic approach for CRC typically involves a multimodal regimen. The human gut …