Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …

Mitochondria are highly dynamic organelles that participate in ATP generation and involve
calcium homeostasis, oxidative stress response, and apoptosis. Dysfunctional or damaged …

Mitochondrial quality control systems are essential for the maintenance of functional
mitochondria. At the organelle level, they include mitochondrial biogenesis, fusion and …

The phospholipid cardiolipin (CL) is an essential constituent of mitochondrial membranes
and plays a role in many mitochondrial processes, including respiration and energy …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Mitophagy is an evolutionarily conserved cellular process which selectively eliminates
dysfunctional mitochondria by targeting them to the autophagosome for degradation …

Owing to the dominant functions of mitochondria in multiple cellular metabolisms and distinct
types of regulated cell death, maintaining a functional mitochondrial network is fundamental …

In the past years, we have learnt that tumors co-evolve with their microenvironment, and that
the active interaction between cancer cells and stromal cells plays a pivotal role in cancer …

Biological aging is an inevitable and independent risk factor for a wide array of chronic
diseases including cardiovascular and metabolic diseases. Ample evidence has established …

Mitochondria are highly dynamic organelles and important for a variety of cellular functions.
They constantly undergo fission and fusion events, referred to as mitochondrial dynamics …