[HTML][HTML] Metazoan micrornas
DP Bartel - Cell, 2018 - cell.com
MicroRNAs (miRNAs) are∼ 22 nt RNAs that direct posttranscriptional repression of mRNA
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
targets in diverse eukaryotic lineages. In humans and other mammals, these small RNAs …
Sexual dimorphism in colon cancer
M Abancens, V Bustos, H Harvey, J McBryan… - Frontiers in …, 2020 - frontiersin.org
A higher incidence of colorectal cancer (CRC) is found in males compared to females.
Young women (18–44 years) with CRC have a better survival outcome compared to men of …
Young women (18–44 years) with CRC have a better survival outcome compared to men of …
The biological functions of miRNAs: lessons from in vivo studies
JA Vidigal, A Ventura - Trends in cell biology, 2015 - cell.com
Despite their clear importance as a class of regulatory molecules, pinpointing the relevance
of individual miRNAs has been challenging. Studies querying miRNA functions by …
of individual miRNAs has been challenging. Studies querying miRNA functions by …
Transfection of microRNA mimics should be used with caution
HY Jin, A Gonzalez-Martin, AV Miletic, M Lai… - Frontiers in …, 2015 - frontiersin.org
Transient transfection of chemically synthesized microRNA (miRNA) mimics is being used
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …
extensively to study the functions and mechanisms of endogenous miRNAs. However, it …
MicroRNAs in the etiology of colorectal cancer: pathways and clinical implications
AM Strubberg, BB Madison - Disease models & …, 2017 - journals.biologists.com
MicroRNAs (miRNAs) are small single-stranded RNAs that repress mRNA translation and
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
trigger mRNA degradation. Of the∼ 1900 miRNA-encoding genes present in the human …
Ablation of miR-10b suppresses oncogene-induced mammary tumorigenesis and metastasis and reactivates tumor-suppressive pathways
The invasive and metastatic properties of many human tumors have been associated with
upregulation of the miRNA miR-10b, but its functional contributions in this setting have not …
upregulation of the miRNA miR-10b, but its functional contributions in this setting have not …
Recovery from heat shock requires the microRNA pathway in Caenorhabditis elegans
DC Pagliuso, DM Bodas, AE Pasquinelli - PLoS genetics, 2021 - journals.plos.org
The heat shock response (HSR) is a highly conserved cellular process that promotes
survival during stress. A hallmark of the HSR is the rapid induction of heat shock proteins …
survival during stress. A hallmark of the HSR is the rapid induction of heat shock proteins …
[HTML][HTML] MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway
R Hu, W Pan, AV Fedulov, W Jester, MR Jones… - The FASEB …, 2014 - ncbi.nlm.nih.gov
Airway smooth muscle (ASM) cells play important physiological roles in the lung, and
abnormal proliferation of ASM directly contributes to the airway remodeling during …
abnormal proliferation of ASM directly contributes to the airway remodeling during …
Noncoding RNAs regulate NF-κB signaling to modulate blood vessel inflammation
Cardiovascular diseases such as atherosclerosis are one of the leading causes of morbidity
and mortality worldwide. The clinical manifestations of atherosclerosis, which include heart …
and mortality worldwide. The clinical manifestations of atherosclerosis, which include heart …
Overexpression of microRNA-10a in germ cells causes male infertility by targeting Rad51 in mouse and human
H Gao, H Wen, C Cao, D Dong, C Yang, S Xie… - Frontiers in …, 2019 - frontiersin.org
Spermatogenesis is a complicated process including spermatogonial stem cells self-
renewal and differentiates into mature spermatozoa. MicroRNAs (miRNAs) as a class of …
renewal and differentiates into mature spermatozoa. MicroRNAs (miRNAs) as a class of …