Nuclease resistance of DNA nanostructures
AR Chandrasekaran - Nature Reviews Chemistry, 2021 - nature.com
DNA nanotechnology has progressed from proof-of-concept demonstrations of structural
design towards application-oriented research. As a natural material with excellent self …
design towards application-oriented research. As a natural material with excellent self …
Host defense peptide mimicking antimicrobial amino acid polymers and beyond: Design, synthesis and biomedical applications
Microbial infections endanger human health and life. Conventional antibiotics has saved
countless human lives, however, is seriously challenged by the quick emergence of …
countless human lives, however, is seriously challenged by the quick emergence of …
Addressing MRSA infection and antibacterial resistance with peptoid polymers
Abstract Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …
antibacterial agents that are not prone to antimicrobial resistance. We prepare protease …
Pharmapolymers in the 21st century: Synthetic polymers in drug delivery applications
The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …
applications, has certainly benefited from the application of synthetic polymers. However …
A field guide to foldamers
The breadth of structure and function displayed by the molecules of biology is remarkable.
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters
PA Wender, DJ Mitchell… - Proceedings of the …, 2000 - National Acad Sciences
Certain proteins contain subunits that enable their active translocation across the plasma
membrane into cells. In the specific case of HIV-1, this subunit is the basic domain Tat49–57 …
membrane into cells. In the specific case of HIV-1, this subunit is the basic domain Tat49–57 …
Peptoid polymers: a highly designable bioinspired material
J Sun, RN Zuckermann - ACS nano, 2013 - ACS Publications
Bioinspired polymeric materials are attracting increasing attention due to significant
advantages over their natural counterparts: the ability to precisely tune their structures over a …
advantages over their natural counterparts: the ability to precisely tune their structures over a …
Peptoids and polypeptoids at the frontier of supra-and macromolecular engineering
In most general terms, polymers and their supramolecular assemblies have been defining
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
life on this planet since its conception. Polymers of nucleic acids carry the code of life and …
Challenge to overcome current limitations of cell-penetrating peptides
The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …
Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications
Although the first polysarcosine (pSar) synthesis by Wesseley et al. was reported almost a
century ago, it was only recently that pSar gained broader attention and is considered a …
century ago, it was only recently that pSar gained broader attention and is considered a …