[HTML][HTML] Spotlight on plasticity-related genes: current insights in health and disease
N Brandt, F Köper, J Hausmann, AU Bräuer - Pharmacology & Therapeutics, 2024 - Elsevier
The development of the central nervous system is highly complex, involving numerous
developmental processes that must take place with high spatial and temporal precision. This …
developmental processes that must take place with high spatial and temporal precision. This …
Plasma membrane phospholipid phosphatase-related proteins as pleiotropic regulators of neuron growth and excitability
J Fuchs, S Bareesel, C Kroon, A Polyzou… - Frontiers in Molecular …, 2022 - frontiersin.org
Neuronal plasma membrane proteins are essential for integrating cell extrinsic and cell
intrinsic signals to orchestrate neuronal differentiation, growth and plasticity in the …
intrinsic signals to orchestrate neuronal differentiation, growth and plasticity in the …
[HTML][HTML] Identification of intrinsic axon growth modulators for intact CNS neurons after injury
Functional deficits persist after spinal cord injury (SCI) because axons in the adult
mammalian central nervous system (CNS) fail to regenerate. However, modest levels of …
mammalian central nervous system (CNS) fail to regenerate. However, modest levels of …
The axonal membrane protein PRG2 inhibits PTEN and directs growth to branches
A Brosig, J Fuchs, F Ipek, C Kroon, S Schrötter… - Cell reports, 2019 - cell.com
In developing neurons, phosphoinositide 3-kinases (PI3Ks) control axon growth and
branching by positively regulating PI3K/PI (3, 4, 5) P 3, but how neurons are able to …
branching by positively regulating PI3K/PI (3, 4, 5) P 3, but how neurons are able to …
PRG-1 regulates synaptic plasticity via intracellular PP2A/β1-integrin signaling
X Liu, J Huai, H Endle, L Schlüter, W Fan, Y Li… - Developmental cell, 2016 - cell.com
Alterations in dendritic spine numbers are linked to deficits in learning and memory. While
we previously revealed that postsynaptic plasticity-related gene 1 (PRG-1) controls …
we previously revealed that postsynaptic plasticity-related gene 1 (PRG-1) controls …
New findings about iron oxide nanoparticles and their different effects on murine primary brain cells
J Neubert, S Wagner, J Kiwit, AU Bräuer… - International journal of …, 2015 - Taylor & Francis
The physicochemical properties of superparamagnetic iron oxide nanoparticles (SPIOs)
enable their application in the diagnostics and therapy of central nervous system diseases …
enable their application in the diagnostics and therapy of central nervous system diseases …
Cooperative interactions of LPPR family members in membrane localization and alteration of cellular morphology
P Yu, C Agbaegbu, DA Malide, X Wu… - Journal of Cell …, 2015 - journals.biologists.com
The lipid phosphate phosphatase-related proteins (LPPRs), also known as plasticity-related
genes (PRGs), are classified as a new brain-enriched subclass of the lipid phosphate …
genes (PRGs), are classified as a new brain-enriched subclass of the lipid phosphate …
[HTML][HTML] Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury
Abstract The Plasticity Related Gene family covers five, brain-specific, transmembrane
proteins (PRG1-5, also termed LPPR1-5) that operate in neuronal plasticity during …
proteins (PRG1-5, also termed LPPR1-5) that operate in neuronal plasticity during …
Systematic expression analysis of plasticity‐related genes in mouse brain development brings PRG4 into play
I Gross, T Tschigor, AL Salman, F Yang… - Developmental …, 2022 - Wiley Online Library
Abstract Background Plasticity‐related genes (Prgs/PRGs) or lipid phosphate phosphatase‐
related proteins (LPPRs) comprise five known members, which have been linked to …
related proteins (LPPRs) comprise five known members, which have been linked to …
Plasticity-related gene 5 promotes spine formation in murine hippocampal neurons
The transmembrane protein plasticity-related genes 3 and 5 (PRG3 and PRG5) increase
filopodial formation in various cell lines, independently of Cdc42. However, information on …
filopodial formation in various cell lines, independently of Cdc42. However, information on …