Many proteins are modified by posttranslational methylation, introduced by a number of
methyltransferases (MTases). Protein methylation plays important roles in modulating …

Proteins are regulated by an incredible array of posttranslational modifications (PTMs).
Methylation of lysine residues on histone proteins is a PTM with well-established roles in …

The posttranslational modification of proteins by arginine methylation is functionally
important, yet the breadth of this modification is not well characterized. Using high-resolution …

Protein arginine methyltransferases (PRMTs) catalyze arginine methylation on both
chromatin-bound and cytoplasmic proteins. Accumulating evidence supports the …

Protein arginine methyltransferases (PRMTs) introduce arginine methylation, a post-
translational modification with the increasingly eminent role in normal physiology and …

Protein arginine methylation plays an important role in regulating protein functions in
different cellular processes, and its dysregulation may lead to a variety of human diseases …

Cells synthesize proteins using 20 standard amino acids and expand their biochemical
repertoire through intricate enzyme-mediated post-translational modifications (PTMs). PTMs …

Protein methylation is a key post-translational modification whose effects on gene
expression have been intensively studied over the last two decades. Recently, renewed …

Eukaryotic elongation factor 1A (eEF1A) is an essential and highly conserved protein
involved in diverse cellular processes, including translation, cytoskeleton organisation …

Methylation is a common biochemical reaction, and a number of methyltransferase (MTase)
enzymes mediate the various methylation events occurring in living cells. Almost all MTases …