Pharmacological properties and health benefits of eugenol: A comprehensive review

MF Nisar, M Khadim, M Rafiq, J Chen… - Oxidative medicine …, 2021 - Wiley Online Library
The biologically active phytochemicals are sourced from edible and medicinally important
plants and are important molecules being used for the formulation of thousands of drugs …

[HTML][HTML] Essential oil eugenol: Sources, extraction techniques and nutraceutical perspectives

AA Khalil, U ur Rahman, MR Khan, A Sahar… - RSC …, 2017 - pubs.rsc.org
Eugenol, a phytogenic bioactive component is frequently found in diversified herbal plants
possessing well-defined functional attributes. Prominent sources of eugenol are clove …

Antidiabetic effects of simple phenolic acids: A comprehensive review

R Vinayagam, M Jayachandran, B Xu - Phytotherapy research, 2016 - Wiley Online Library
Diabetes mellitus (DM) has become a major public health threat across the globe. Current
antidiabetic therapies are based on synthetic drugs that very often have side effects. It has …

[HTML][HTML] Eugenol, a component of holy basil (Tulsi) and common spice clove, inhibits the interaction between SARS-CoV-2 spike S1 and ACE2 to induce therapeutic …

RK Paidi, M Jana, S Raha, M McKay, M Sheinin… - Journal of Neuroimmune …, 2021 - Springer
Abstract Spike S1 of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
binds to angiotensin-converting enzyme 2 (ACE2) on host cells to enter the cell and initiate …

A systematic review on anti-diabetic plant essential oil compounds: dietary sources, effects, molecular mechanisms, and safety

GR Gandhi, VE Hillary, PJ Antony… - Critical reviews in …, 2023 - Taylor & Francis
Type 2 diabetes mellitus (T2DM) is a multifaceted metabolic syndrome defined through the
dysfunction of pancreatic β-cells driven by a confluence of genetic and environmental …

[HTML][HTML] Antidiabetic potential of volatile cinnamon oil: A review and exploration of mechanisms using in silico molecular docking simulations

N Stevens, K Allred - Molecules, 2022 - mdpi.com
Cinnamon has been used as a flavoring and medicinal agent for centuries. Much research
has focused on cinnamon bark powder, which contains antioxidants, flavonoids …

Eugenol ameliorates insulin resistance, oxidative stress and inflammation in high fat-diet/streptozotocin-induced diabetic rat

B Al-Trad, H Alkhateeb, W Alsmadi, M Al-Zoubi - Life sciences, 2019 - Elsevier
Background Eugenol, a phenolic compound present in many plant essential oils,
demonstrated anti-diabetic activity but the underlying mechanisms are not fully understood …

Cinnamaldehyde and eugenol attenuates collagen induced arthritis via reduction of free radicals and pro-inflammatory cytokines

S Mateen, S Shahzad, S Ahmad, SS Naeem, S Khalid… - Phytomedicine, 2019 - Elsevier
Background Rheumatoid arthritis (RA) is an inflammatory autoimmune disease which leads
to bone and cartilage erosion. Oxidative stress and pro-inflammatory cytokines plays crucial …

[HTML][HTML] Ethyl Acetate Fraction of Helianthus tuberosus L. Induces Anti-Diabetic, and Wound-Healing Activities in Insulin-Resistant Human Liver Cancer and Mouse …

AVA Mariadoss, SJ Park, K Saravanakumar… - Antioxidants, 2021 - mdpi.com
Traditional, complementary, and integrative medicine are globally accepted alternative
methods for the treatment of diabetes mellitus (DM). However, the mechanism of anti …

[HTML][HTML] Eugenol reduces LDL cholesterol and hepatic steatosis in hypercholesterolemic rats by modulating TRPV1 receptor

AA Harb, YK Bustanji, IM Almasri, SS Abdalla - Scientific Reports, 2019 - nature.com
Eugenol, a component of essential oils of medicinal and food plants, has a hypolipidemic
effect in experimental animals although its mechanism of action is still unclear. This study …