[HTML][HTML] Programming assembly of biomimetic exosomes: an emerging theranostic nanomedicine platform

X Xu, L Xu, C Wen, J Xia, Y Zhang, Y Liang - Materials Today Bio, 2023 - Elsevier
Exosomes have emerged as a promising cell-free therapeutic approach. However,
challenges in large-scale production, quality control, and heterogeneity must be overcome …

Extracellular‐vesicle‐based drug delivery systems for enhanced antitumor therapies through modulating the cancer‐immunity cycle

T Yong, Z Wei, L Gan, X Yang - Advanced Materials, 2022 - Wiley Online Library
Although immunotherapy harnessing activity of the immune system against tumors has
made great progress, the treatment efficacy remains limited in most cancers. Current …

Osteoblast/osteoclast and immune cocktail therapy of an exosome/drug delivery multifunctional hydrogel accelerates fracture repair

B Mi, L Chen, Y Xiong, Y Yang, AC Panayi, H Xue… - ACS …, 2022 - ACS Publications
The osteoblast/osteoclast and M1/M2 macrophage ratios play critical roles in delayed
fracture healing. Robust osteoblast differentiation and M2 macrophage polarization can …

Recent progresses in exosome-based systems for targeted drug delivery to the brain

S Bashyal, C Thapa, S Lee - Journal of Controlled Release, 2022 - Elsevier
Despite the multiple ongoing and novel initiatives for developing brain-targeted drug
delivery systems, insurmountable obstacles remain. A perfect drug delivery device that can …

Plant exosome nanovesicles (PENs): green delivery platforms

M Cao, N Diao, X Cai, X Chen, Y Xiao, C Guo… - Materials …, 2023 - pubs.rsc.org
Natural plants have been gaining increasing attention in biomedical research due to their
numerous benefits. One of the plant's components, plant exosome-derived vesicles, are …

Bioengineered exosomal-membrane-camouflaged abiotic nanocarriers: neurodegenerative diseases, tissue engineering and regenerative medicine

D Lopes, J Lopes, M Pereira-Silva, D Peixoto… - Military Medical …, 2023 - Springer
A bio-inspired strategy has recently been developed for camouflaging nanocarriers with
biomembranes, such as natural cell membranes or subcellular structure-derived …

Exosomes engineering and their roles as therapy delivery tools, therapeutic targets, and biomarkers

N Kučuk, M Primožič, Ž Knez, M Leitgeb - International journal of …, 2021 - mdpi.com
Exosomes are becoming increasingly important therapeutic biomaterials for use in a variety
of therapeutic applications due to their unique characteristics, especially due to the …

Harnessing the therapeutic potential of extracellular vesicles for biomedical applications using multifunctional magnetic nanomaterials

L Yang, KD Patel, C Rathnam, R Thangam, Y Hou… - Small, 2022 - Wiley Online Library
Extracellular vesicles (eg, exosomes) carrying various biomolecules (eg, proteins, lipids,
and nucleic acids) have rapidly emerged as promising platforms for many biomedical …

Artificial exosomes for translational nanomedicine

YJ Li, JY Wu, J Liu, W Xu, X Qiu, S Huang… - Journal of …, 2021 - Springer
Exosomes are lipid bilayer membrane vesicles and are emerging as competent
nanocarriers for drug delivery. The clinical translation of exosomes faces many challenges …

Recent progress in the effect of magnetic iron oxide nanoparticles on cells and extracellular vesicles

Y Chen, S Hou - Cell Death Discovery, 2023 - nature.com
At present, iron oxide nanoparticles (IONPs) are widely used in the biomedical field. They
have unique advantages in targeted drug delivery, imaging and disease treatment …