The comparative toxicogenomics database: update 2019

AP Davis, CJ Grondin, RJ Johnson… - Nucleic acids …, 2019 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) is a premier
public resource for literature-based, manually curated associations between chemicals …

The comparative toxicogenomics database: update 2013

AP Davis, CG Murphy, R Johnson, JM Lay… - Nucleic acids …, 2013 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD; http://ctdbase. org/) provides
information about interactions between environmental chemicals and gene products and …

The comparative toxicogenomics database: update 2011

AP Davis, BL King, S Mockus, CG Murphy… - Nucleic acids …, 2010 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD) is a public resource that
promotes understanding about the interaction of environmental chemicals with gene …

MEDIC: a practical disease vocabulary used at the Comparative Toxicogenomics Database

AP Davis, TC Wiegers, MC Rosenstein, CJ Mattingly - Database, 2012 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD) is a public resource that
promotes understanding about the effects of environmental chemicals on human health …

A CTD–Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug–disease and drug–phenotype interactions

AP Davis, TC Wiegers, PM Roberts, BL King, JM Lay… - Database, 2013 - academic.oup.com
Improving the prediction of chemical toxicity is a goal common to both environmental health
research and pharmaceutical drug development. To improve safety detection assays, it is …

Association between urinary phthalate metabolites and risk of breast cancer and uterine leiomyoma

Z Fu, F Zhao, K Chen, J Xu, P Li, D Xia, Y Wu - Reproductive Toxicology, 2017 - Elsevier
Objective The objective of this study was to systematically assess the association between
urinary phthalate metabolites and risk of breast cancer and uterine leiomyoma. Methods …

[HTML][HTML] Gene-environment interactions within a precision environmental health framework

AA Motsinger-Reif, DM Reif, FS Akhtari, JS House… - Cell Genomics, 2024 - cell.com
Understanding the complex interplay of genetic and environmental factors in disease
etiology and the role of gene-environment interactions (GEIs) across human development …

The curation paradigm and application tool used for manual curation of the scientific literature at the Comparative Toxicogenomics Database

AP Davis, TC Wiegers, CG Murphy, CJ Mattingly - Database, 2011 - academic.oup.com
Abstract The Comparative Toxicogenomics Database (CTD) is a public resource that
promotes understanding about the effects of environmental chemicals on human health …

[HTML][HTML] Chemical Mixtures in Household Environments: In Silico Predictions and In Vitro Testing of Potential Joint Action on PPARγ in Human Liver Cells

CK Carberry, T Turla, LE Koval, H Hartwell, RC Fry… - Toxics, 2022 - mdpi.com
There are thousands of chemicals that humans can be exposed to in their everyday
environments, the majority of which are currently understudied and lack substantial testing …

[PDF][PDF] 毒理基因组学研究进展

陆韻, 侯凌燕, 胡洪营, 李莉 - 2010 - jeesci.com
毒理基因组学是利用最新的基因组学技术来进行毒理学研究的新兴学科. 它能够快速全面地检测
出化合物和生物体相互作用后的全基因组表达的变化, 再通过生物信息学的方法对化合物的毒性 …