Neutrophil nucleus: shaping the past and the future
J Salafranca, JK Ko, AK Mukherjee… - Journal of Leukocyte …, 2023 - academic.oup.com
Neutrophils are innate immune cells that are key to protecting the host against infection and
maintaining body homeostasis. However, if dysregulated, they can contribute to disease …
maintaining body homeostasis. However, if dysregulated, they can contribute to disease …
Experimental and computational framework for a dynamic protein atlas of human cell division
Essential biological functions, such as mitosis, require tight coordination of hundreds of
proteins in space and time. Localization, the timing of interactions and changes in cellular …
proteins in space and time. Localization, the timing of interactions and changes in cellular …
Building cell models and simulations from microscope images
RF Murphy - Methods, 2016 - Elsevier
The use of fluorescence microscopy has undergone a major revolution over the past twenty
years, both with the development of dramatic new technologies and with the widespread …
years, both with the development of dramatic new technologies and with the widespread …
[HTML][HTML] Orientation-invariant autoencoders learn robust representations for shape profiling of cells and organelles
Cell and organelle shape are driven by diverse genetic and environmental factors and thus
accurate quantification of cellular morphology is essential to experimental cell biology …
accurate quantification of cellular morphology is essential to experimental cell biology …
[HTML][HTML] Inferring cell state by quantitative motility analysis reveals a dynamic state system and broken detailed balance
Cell populations display heterogeneous and dynamic phenotypic states at multiple scales.
Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a …
Similar to molecular features commonly used to explore cell heterogeneity, cell behavior is a …
Evaluation of methods for generative modeling of cell and nuclear shape
Motivation Cell shape provides both geometry for, and a reflection of, cell function.
Numerous methods for describing and modeling cell shape have been described, but …
Numerous methods for describing and modeling cell shape have been described, but …
Next‐generation pathology detection of T cell–antigen‐presenting cell immune synapses in human liver allografts
MA Wood‐Trageser, D Lesniak, A Gambella… - Hepatology, 2023 - journals.lww.com
Next‐generation pathology detection of T cell–antigen‐presen... : Hepatology Next‐generation
pathology detection of T cell–antigen‐presenting cell immune synapses in human liver …
pathology detection of T cell–antigen‐presenting cell immune synapses in human liver …
[HTML][HTML] An image-based data-driven analysis of cellular architecture in a developing tissue
J Hartmann, M Wong, E Gallo, D Gilmour - elife, 2020 - elifesciences.org
Quantitative microscopy is becoming increasingly crucial in efforts to disentangle the
complexity of organogenesis, yet adoption of the potent new toolbox provided by modern …
complexity of organogenesis, yet adoption of the potent new toolbox provided by modern …
Building a 3d integrated cell
We present a conditional generative model for learning variation in cell and nuclear
morphology and predicting the location of subcellular structures from 3D microscopy …
morphology and predicting the location of subcellular structures from 3D microscopy …
[HTML][HTML] Modelling cell shape in 3D structured environments: A quantitative comparison with experiments
R Link, M Jaggy, M Bastmeyer… - PLOS Computational …, 2024 - journals.plos.org
Cell shape plays a fundamental role in many biological processes, including adhesion,
migration, division and development, but it is not clear which shape model best predicts …
migration, division and development, but it is not clear which shape model best predicts …