[PDF][PDF] One year in review 2020: pathogenesis of rheumatoid arthritis

D Giannini, M Antonucci, F Petrelli, S Bilia… - Clin Exp …, 2020 - clinexprheumatol.org
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease influenced by both
genetic, epigenetic and environmental factors. The discovery of new gene polymorphisms …

Cardiovascular effects of approved drugs for rheumatoid arthritis

F Atzeni, J Rodríguez-Carrio, CD Popa… - Nature Reviews …, 2021 - nature.com
The risk of cardiovascular disease is increased in patients with rheumatoid arthritis
compared with the general population owing to the influence of traditional and non …

IL-6: linking chronic inflammation and vascular calcification

R López-Mejías, MA González-Gay - Nature Reviews Rheumatology, 2019 - nature.com
New data highlight the contribution of IL-6 to vascular calcification in chronic inflammation.
Given that increased vascular calcification and accelerated atherosclerosis occur in patients …

Genome‐Wide Assessment of Shared Genetic Architecture Between Rheumatoid Arthritis and Cardiovascular Diseases

Y Guo, W Chung, Z Shan, Z Zhu… - Journal of the …, 2023 - Am Heart Assoc
Background Patients with rheumatoid arthritis (RA) have a 2‐to 10‐fold increased risk of
cardiovascular disease (CVD), but the biological mechanisms and existence of causality …

Exploring potential shared genetic influences between rheumatoid arthritis and blood lipid levels

M Kasher, SS Cherny, G Livshits… - Atherosclerosis, 2022 - Elsevier
Background and aims The association between rheumatoid arthritis (RA) and blood lipid
levels has often been described as paradoxical, despite the strong association between RA …

Diagnosis and management of cardiovascular risk in rheumatoid arthritis: main challenges and research agenda

F Atzeni, S Maiani, M Corda… - Expert Review of …, 2023 - Taylor & Francis
Introduction Rheumatoid arthritis (RA) exhibit a cardiovascular (CV) risk that is 1.5–2.0 times
higher compared to the general population. This CV risk excess is likely caused by the …

[HTML][HTML] Rheumatoid Arthritis Has Won the Battle but Not the War: How Many Joints Will We Save Tomorrow?

VV Oberemok, O Andreeva, K Laikova, E Alieva… - Medicina, 2023 - mdpi.com
Rheumatoid arthritis refers to joint diseases of unclear etiology whose final stages can lead
to unbearable pain and complete immobility of the affected joints. As one of the most widely …

[HTML][HTML] Osteoprotegerin and MTHFR gene variations in rheumatoid arthritis: association with disease susceptibility and markers of subclinical atherosclerosis

A Arida, A Nezos, I Papadaki, PP Sfikakis… - Scientific Reports, 2022 - nature.com
We aimed to explore whether the rs2073618 variant (G1181C) of the osteoprotegerin (OPG)
gene and the methylenetetrahydrofolate reductase (MTHFR) rs1801131 (A1298AC) and …

[HTML][HTML] Relationship between rheumatoid arthritis and cardiovascular comorbidity, causation or co-occurrence: A Mendelian randomization study

M Wang, C Chao, K Mei, D Di, Y Qian… - Frontiers in …, 2023 - frontiersin.org
Background In recent years, the incidence rates of rheumatoid arthritis (RA) and heart
disease (HD) have noticeably increased worldwide. Previous studies have found that …

[HTML][HTML] Accelerated atherosclerosis in premenopausal women with rheumatoid arthritis–a 15-year follow-up study

MK Krajnc, R Hojs, I Holc, Ž Knez… - Bosnian journal of basic …, 2021 - ncbi.nlm.nih.gov
Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased
mortality and morbidity due to the higher risks for cardiovascular disease. Traditional risk …