Consanguinity is a deeply rooted social trend among one-fifth of the world population mostly
residing in the Middle East, West Asia and North Africa, as well as among emigrants from …

Abstract Alpha-thalassemia (α-thal) is probably the most prevalent monogenic condition in
the world. Deletions are the most common types of mutations in α-thal, followed by point …

Thalassemia poses a major public health concern in Bangladesh with a high prevalence of
carriers. However, there is a substantial knowledge gap regarding its epidemiology, clinical …

Background Beta thalassemia is a preventable disease. Iran has about 20,000 Patients who
are homozygote for β-thalassaemia and 3,750,000 carriers. The aim of this study was to …

Background: Thalassemia syndromes are the most prevalent single gene disorders in Iran.
This study aimed to evaluate the effect of different types of beta-globin gene mutations, co …

We hypothesized that consanguineous marriage will remain a risk factor for pregnancy
outcome and offspring mortality, but the development in demographic, socioeconomic …

Thalassemia is one of the most prevalent genetic disorders in Iran. The birth of a child with
thalassemia major is associated with many problems for the family, and society. In the …

Thalassemia and hemodialysis patients are at risk of blood-transmitted infections due to
their long-term need for blood transfusion. Nowadays, control of viral infections, including …

Background Premarital medical examination (PME) compliance rate has dropped drastically
since it became voluntary in China in 2003. This study aimed to establish a prediction model …

This study aimed to characterize the molecular spectrum of β-thalassemia (β-thal) mutations
and evaluate the services available for prenatal diagnosis (PND) among the Sistani …