Thrombophilia is considered as a condition predisposing to the development of thrombosis.
Arterial thrombosis usually occurs after the erosion or rupture of an atherosclerotic plaque …

Although venous thrombosis has been traditionally associated with stasis and
hypercoagulability, arterial thrombosis is mainly associated with heightened platelet …

New clinical, laboratory and experimental insights, since the 1999 publication of the
Sapporo preliminary classification criteria for antiphospholipid syndrome (APS), had been …

One of the conclusions of the subcommittee meeting on Lupus Anticoagulant/Phospholipid
dependent antibodies, held in Geneva on 2007, was the need to update the guidelines on …

Objective. To develop and validate a risk score [global APS score (GAPSS)] derived from the
combination of independent risk for thrombosis and pregnancy loss (PL), taking into account …

Background Arterial thrombosis is a major clinical manifestation of the antiphospholipid
syndrome, which is an autoimmune disease found mostly in young women. Although the …

Thrombophilia can be identified in about half of all patients presenting with venous
thrombosis. Testing has increased tremendously for various indications, but whether the …

Sepsis is a systemic host response to invasive infection by bacteria. Despite treatment with
antibiotics, current mortality rates are in the range of 20%-25%, which makes sepsis the …

Early pregnancy loss is the most common pregnancy complication. About 15% of
pregnancies result in pregnancy loss and 1% of women experience recurrent miscarriage …

Background: The antiphospholipid syndrome (APS) is an important cause of acquired
thromboembolic complications and pregnancy morbidity. Its diagnosis is based on clinical …