Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of
the accumulation of fluids outside of the blood vessels, causing rapid swelling of tissues in …

Hereditary angioedema with C1 Inhibitor deficiency (C1-INH-HAE) is caused by a
constellation of variants of the SERPING1 gene (n= 809; 1,494 pedigrees), accounting for …

The evolution in the knowledge of rare genetic diseases such as hereditary angioedema
(HAE) has increased at a parallel pace with the development of new molecular tools. The …

Hereditary angioedema (HAE) is an uncommon genetic disorder characterized by recurrent
episodes of edema involving subcutaneous tissue and submucosa. The pathogenesis of …

Hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE) is a rare and life-
threatening condition characterized by recurrent localized edema. We conducted a …

Biochemical studies performed during the last decades resulted in the development of
various innovative medicinal products for hereditary angioedema (HAE). These therapeutic …

Introduction Hereditary angioedema (HAE) is a rare genetic disorder characterized by
recurrent edema and predominantly caused by the dysregulation of the kinin-kallikrein …

Background Primary angioedema (PA) is a complex disorder, presenting multiple hereditary
(hereditary angioedema) and acquired subtypes (acquired angioedema). Despite a very …

The validation of biomarkers for the contact system activation could be beneficial in
differentiating bradykinin–from histaminergic-mediated angioedema. Currently, the available …

Abstract Purpose of Review Hereditary angioedema (HAE) is a disorder affecting bradykinin
regulation presenting as recurrent cutaneous or mucosal swelling. Treatment options …