The impact of sensory neuropathy and inflammation on epithelial wound healing in diabetic corneas

XY Fu-Shin, PSY Lee, L Yang, N Gao, Y Zhang… - Progress in retinal and …, 2022 - Elsevier
Diabetic peripheral neuropathy (DPN) is the most common complication of diabetes, with
several underlying pathophysiological mechanisms, some of which are still uncertain. The …

Corneal nerves in health and disease

MA Al-Aqaba, VK Dhillon, I Mohammed… - Progress in retinal and …, 2019 - Elsevier
The cornea is the most sensitive structure in the human body. Corneal nerves adapt to
maintain transparency and contribute to corneal health by mediating tear secretion and …

In vivo confocal microscopy of corneal nerves in health and disease

A Cruzat, Y Qazi, P Hamrah - The ocular surface, 2017 - Elsevier
In vivo confocal microscopy (IVCM) is becoming an indispensable tool for studying corneal
physiology and disease. Enabling the dissection of corneal architecture at a cellular level …

Emerging biomarkers, tools, and treatments for diabetic polyneuropathy

GJ Bönhof, C Herder, A Strom, N Papanas… - Endocrine …, 2019 - academic.oup.com
Diabetic neuropathy, with its major clinical sequels, notably neuropathic pain, foot ulcers,
and autonomic dysfunction, is associated with substantial morbidity, increased risk of …

[HTML][HTML] Diabetic complications in the cornea

AV Ljubimov - Vision research, 2017 - Elsevier
Diabetic corneal alterations, such as delayed epithelial wound healing, edema, recurrent
erosions, neuropathy/loss of sensitivity, and tear film changes are frequent but …

Сахарный диабет 2 типа у взрослых

ИИ Дедов, МВ Шестакова, АЮ Майоров… - Сахарный …, 2020 - dia-endojournals.ru
1.1 ОПРЕДЕЛЕНИЕ ЗАБОЛЕВАНИЯ ИЛИ СОСТОЯНИЯ (ГРУППЫ ЗАБОЛЕВАНИЙ ИЛИ
СОСТОЯНИЙ) 7 1.2 ЭТИОЛОГИЯ И ПАТОГЕНЕЗ ЗАБОЛЕВАНИЯ ИЛИ СОСТОЯНИЯ …

[HTML][HTML] Focus: Sensory biology and pain: Corneal innervation and sensation: The eye and beyond

AY Yang, J Chow, J Liu - The Yale journal of biology and medicine, 2018 - ncbi.nlm.nih.gov
The cornea is one of the most densely innervated and sensitive tissues in the body. In
addition to their important sensory functions, corneal nerves induce reflex tear production …

Mechanistic investigations of diabetic ocular surface diseases

Q Zhou, L Yang, Q Wang, Y Li, C Wei… - Frontiers in …, 2022 - frontiersin.org
With the global prevalence of diabetes mellitus over recent decades, more patients suffered
from various diabetic complications, including diabetic ocular surface diseases that may …

Surrogate markers of small fiber damage in human diabetic neuropathy

C Quattrini, M Tavakoli, M Jeziorska, P Kallinikos… - Diabetes, 2007 - Am Diabetes Assoc
Surrogate markers of diabetic neuropathy are being actively sought to facilitate the
diagnosis, measure the progression, and assess the benefits of therapeutic intervention in …

Corneal confocal microscopy: a novel noninvasive test to diagnose and stratify the severity of human diabetic neuropathy

M Tavakoli, C Quattrini, C Abbott, P Kallinikos… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE The accurate quantification of human diabetic neuropathy is important to define
at-risk patients, anticipate deterioration, and assess new therapies. RESEARCH DESIGN …