[HTML][HTML] Dual-functional composite scaffolds for inhibiting infection and promoting bone regeneration

Y Cui, H Liu, Y Tian, Y Fan, S Li, G Wang, Y Wang… - Materials Today Bio, 2022 - Elsevier
The treatment of infected bone defects is an intractable problem in orthopedics. It comprises
two critical parts, namely that of infection control and bone defect repair. According to these …

Advances in CAR‐Engineered Immune Cell Generation: Engineering Approaches and Sourcing Strategies

Z Chen, Y Hu, H Mei - Advanced Science, 2023 - Wiley Online Library
Chimeric antigen receptor T‐cell (CAR‐T) therapy has emerged as a highly efficacious
treatment modality for refractory and relapsed hematopoietic malignancies in recent years …

Engineering 3D-printed strontium-titanium scaffold-integrated highly bioactive serum exosomes for critical bone defects by osteogenesis and angiogenesis

H Liu, R Gu, W Li, L Zeng, Y Zhu, BC Heng… - … Applied Materials & …, 2023 - ACS Publications
Currently, healing of large bone defects faces significant challenges such as a bulk of bone
regeneration and revascularization on the bone defect region. Here, a “cell-free scaffold …

7, 8-Dihydroxyflavone modulates bone formation and resorption and ameliorates ovariectomy-induced osteoporosis

F Xue, Z Zhao, Y Gu, J Han, K Ye, Y Zhang - Elife, 2021 - elifesciences.org
Imbalances in bone formation and resorption cause osteoporosis. Mounting evidence
supports that brain-derived neurotrophic factor (BDNF) implicates in this process. 7, 8 …

Interaction of iron oxide nanoparticles with macrophages is influenced distinctly by “self” and “non-self” biological identities

Y Portilla, V Mulens-Arias, N Daviu… - … Applied Materials & …, 2023 - ACS Publications
Upon contact with biological fluids like serum, a protein corona (PC) complex forms on iron
oxide nanoparticles (IONPs) in physiological environments and the proteins it contains …

Curculigoside attenuates oxidative stress and osteoclastogenesis via modulating Nrf2/NF-κB signaling pathway in RAW264. 7 cells

M Liu, S Liu, Q Zhang, Y Fang, Y Yu, L Zhu… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Curculigo orchioides Gaertn is used for the
treatment of impotence, atrophic debility of bones (osteoporosis), limb limpness, and arthritis …

Premetastatic Niche Mimicking Bone‐On‐A‐Chip: A Microfluidic Platform to Study Bone Metastasis in Cancer Patients

X Ji, HP Bei, G Zhong, H Shao, X He, X Qian, Y Zhang… - Small, 2023 - Wiley Online Library
Primary cancer modulates the bone microenvironment to sow the seeds of dormancy and
metastasis in tumor cells, leading to multiple organ metastasis and death. In this study, 3D …

The potential therapeutic effects of hydroxypropyl cellulose on acute murine colitis induced by DSS

X Li, H Lv, F Shi, J Song, Z Zhang - Carbohydrate polymers, 2022 - Elsevier
In this study, high-substituted hydroxypropyl cellulose (HHPC) and low-substituted
hydroxypropyl cellulose (LHPC) were orally administered (150 or 300 mg/kg) to investigate …

Poly (dimethyl diallyl ammonium chloride) incorporated multilayer coating on biodegradable AZ31 magnesium alloy with enhanced resistance to chloride corrosion …

B Zhang, R Yao, MF Maitz, G Mao, Z Hou, H Yu… - Chemical Engineering …, 2021 - Elsevier
Controlled corrosion and proper biological response are key demands for biodegradable
Mg-alloy based vascular stents. To achieve those properties, herein, a chemical conversion …

Long noncoding RNA Malat1 protects against osteoporosis and bone metastasis

Y Zhao, J Ning, H Teng, Y Deng, M Sheldon… - Nature …, 2024 - nature.com
MALAT1, one of the few highly conserved nuclear long noncoding RNAs (lncRNAs), is
abundantly expressed in normal tissues. Previously, targeted inactivation and genetic …