Heparin: past, present, and future

EI Oduah, RJ Linhardt, ST Sharfstein - Pharmaceuticals, 2016 - mdpi.com
Heparin, the most widely used anticoagulant drug in the world today, remains an animal-
derived product with the attendant risks of adulteration and contamination. A contamination …

Heparin and low-molecular-weight heparin

E Gray, B Mulloy, TW Barrowcliffe - Thrombosis and …, 2008 - thieme-connect.com
Heparin is one of the oldest biological medicines, and has an established place in the
prevention and treatment of venous thrombosis. Low-molecular-weight heparins (LMWH) …

[HTML][HTML] Society for Immunotherapy of Cancer (SITC) clinical practice guideline on immune checkpoint inhibitor-related adverse events

JR Brahmer, H Abu-Sbeih, PA Ascierto… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) are the standard of care for the treatment of several
cancers. While these immunotherapies have improved patient outcomes in many clinical …

Prevention of venous thromboembolism: American College of Chest Physicians evidence-based clinical practice guidelines

WH Geerts, D Bergqvist, GF Pineo, JA Heit… - Chest, 2008 - Elsevier
This article discusses the prevention of venous thromboembolism (VTE) and is part of the
Antithrombotic and Thrombolytic Therapy: American College of Chest Physicians Evidence …

[图书][B] Te Linde's operative gynecology

HW Jones, JA Rock - 2015 - books.google.com
Te Linde's Operative Gynecology has been the premier text in the field of gynecologic
surgery for more than 60 years. This text covers all of the aspects of gynecologic surgery …

Efficacy of prophylactic low–molecular weight heparin for ambulatory patients with advanced pancreatic cancer: outcomes from the CONKO-004 trial

U Pelzer, B Opitz, G Deutschinoff, M Stauch… - Journal of Clinical …, 2015 - ascopubs.org
Purpose Advanced pancreatic cancer (APC), in addition to its high mortality, accounts for the
highest rates of venous thromboembolic events (VTEs). Enoxaparin, a low–molecular weight …

Systematic review: the Trousseau syndrome revisited: should we screen extensively for cancer in patients with venous thromboembolism?

M Carrier, G Le Gal, PS Wells, D Fergusson… - Annals of internal …, 2008 - acpjournals.org
Background: Identifying previously undiagnosed cancer in patients with newly diagnosed
venous thromboembolism (VTE) is important. Screening for malignant conditions can …

SST0001, a chemically modified heparin, inhibits myeloma growth and angiogenesis via disruption of the heparanase/syndecan-1 axis

JP Ritchie, VC Ramani, Y Ren, A Naggi, G Torri… - Clinical Cancer …, 2011 - AACR
Purpose: Heparanase promotes myeloma growth, dissemination, and angiogenesis through
modulation of the tumor microenvironment, thus highlighting the potential of therapeutically …

Platelets promote tumor growth and metastasis via direct interaction between Aggrus/podoplanin and CLEC-2

S Takagi, S Sato, T Oh-hara, M Takami, S Koike… - PloS one, 2013 - journals.plos.org
The platelet aggregation-inducing factor Aggrus, also known as podoplanin, is frequently
upregulated in several types of tumors and enhances hematogenous metastasis by …

Procoagulant mechanisms in tumour cells

A Falanga, M Panova-Noeva, L Russo - Best practice & research Clinical …, 2009 - Elsevier
Pathogenesis of the prothrombotic state of cancer patients is due, at least in part, to the
ability of cancer cells to activate the coagulation system. Several complex and not fully …